Mortality trends in Kazakhstan: insights from a million of deaths from 2014 to 2022.

Publication date: Jul 03, 2025

Kazakhstan’s healthcare system and population health have changed significantly between 2014 and 2022, especially due to the COVID-19 pandemic. This study analyzes mortality trends during this period to better understand the health challenges and regional differences that have emerged, addressing a gap in comprehensive research. We analyzed mortality data from Kazakhstan’s Unified National Electronic Health System (2014-2022), calculating age-standardized mortality rates and years of life lost. Regional trends were assessed using linear regression. Overall mortality increased from 550. 84 to 678. 37 per 100,000 between 2014-2022, with significant regional variations. “Other disorders of the brain” emerged as a leading cause of premature mortality. COVID-19 significantly disrupted mortality patterns in 2020-2021. Mortality rates were consistently higher in males across most age groups, with a sharp increase after age 55, while “other disorders of the brain” emerged as a leading cause of premature mortality. Kazakhstan faces evolving mortality challenges, with stark regional disparities and a concerning rise in neurological disorders. These findings underscore the need for targeted public health interventions and improved cause-of-death reporting.

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Concepts Keywords
Healthcare Adolescent
Kazakhstan Adult
Pandemic Aged
Aged, 80 and over
Cause of Death
Cause of death
Child
Child, Preschool
COVID-19
Female
Humans
Infant
Infant, Newborn
Kazakhstan
Kazakhstan
Life Expectancy
Male
Middle Aged
Mortality
Mortality
Mortality, Premature
Trend
Young Adult

Semantics

Type Source Name
disease MESH COVID-19 pandemic
drug DRUGBANK Tropicamide
disease MESH premature mortality
disease MESH neurological disorders
disease MESH death
pathway REACTOME Reproduction
disease MESH cause of death
disease MESH lifestyle
disease IDO country
drug DRUGBANK Indoleacetic acid
disease MESH cancers
disease MESH strokes
disease MESH Encephalopathy
disease MESH causes

Original Article

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