Publication date: Jul 08, 2025
The study identifies a connection between the loss of E-cadherin, estrogen receptor- (ER), and gastrin-releasing peptide receptor (GRPR), which collectively contribute to the progression of melanoma in female patients. These molecular interactions are associated with an increased likelihood of melanoma spreading in women compared to men. Researchers emphasize the significance of this pathway in understanding why certain cancers behave differently based on sex.
| Concepts | Keywords |
|---|---|
| 2025author | Cadherin |
| Cancers | Cancers |
| Estrogen | Chiang |
| Geneonline | Driven |
| Womenby | Estrogen |
| Links | |
| Loss | |
| Mark | |
| Melanoma | |
| Metastasis | |
| Molecular | |
| Pathway | |
| Receptor | |
| Women |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | cancer |
| disease | MESH | Metastasis |
| pathway | KEGG | Melanoma |
| disease | MESH | Melanoma |
Original Article
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