Gallbladder metastasis in invasive ductal breast cancer with concurrent gallstones and gallbladder carcinoma.

Publication date: Jul 08, 2025

The gallbladder is an uncommon location for tumor metastases. Breast cancer seldom spreads to the gallbladder, although melanoma and renal cell tumors typically do. We report a case of a 58-year-old woman with chronic cholecystitis caused by gallstones. Following a laparoscopic cholecystectomy, a nodule was discovered on the gallbladder wall. Based on her medical history and pathological tissue molecular typing, the diagnosis was determined to be gallbladder metastasis of invasive breast ductal carcinoma, with a negative hormone receptor. Two years prior, the patient had undergone a modified radical mastectomy for left breast cancer. The postoperative pathology revealed grade III invasive ductal carcinoma, pT2N1M0, and a negative hormone receptor. This case report highlights the rare occurrence of invasive breast ductal carcinoma metastasizing to the gallbladder.

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Concepts Keywords
Cancer Gallbladder cancer
Gallbladder Gallstones
Postoperative Metastatic breast cancer
Pt2n1m0
Rare

Semantics

Type Source Name
disease MESH metastasis
disease MESH breast cancer
pathway KEGG Breast cancer
disease MESH tumor
disease MESH melanoma
pathway KEGG Melanoma
disease MESH cholecystitis
disease MESH ductal carcinoma
pathway REACTOME Reproduction
drug DRUGBANK Coenzyme M
disease MESH death
disease MESH lymph node metastases
disease MESH lobular carcinoma
disease MESH lung cancer
disease MESH Gallbladder cancer
disease MESH reproductive history
drug DRUGBANK Capecitabine
disease MESH ankylosis
disease MESH thrombus
drug DRUGBANK Cysteamine
disease MESH noma
disease MESH inflammation
drug DRUGBANK Trestolone
disease MESH clinical relevance
disease MESH carcinoma
disease MESH lifestyle
disease MESH hepatocellular carcinoma
pathway KEGG Hepatocellular carcinoma
drug DRUGBANK Phenobarbital
disease MESH lymphoma
drug DRUGBANK Pentaerythritol tetranitrate
disease MESH acute ischemic stroke
disease MESH Stroke

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