Publication date: Jul 09, 2025
Diffuse idiopathic skeletal hyperostosis (DISH) is increasingly recognized as a structural cause of dysphagia due to anterior cervical osteophyte formation, yet its clinical risk factors, severity determinants, and laterality patterns remain poorly understood. This study aims to investigate the associations between cervical DISH presence, severity, and laterality with clinical, metabolic, and nutritional factors in patients presenting with dysphagia. This was a retrospective observational study including 208 dysphagia patients who underwent head and neck CT imaging between 2014 and 2023. DISH was diagnosed using the Resnick criteria, and severity was classified based on osteophyte thickness ( 7 mm = severe). Laterality was categorized as midline, right-sided, left-sided, or bilateral. Clinical, metabolic, and nutritional variables were compared between DISH and non-DISH groups using t-tests, Chi-square tests, and logistic regression models. Multivariate analyses were performed to identify independent predictors of DISH presence and severity. DISH was present in 81 patients (38. 9%), who were significantly older than non-DISH patients (75. 2 +/- 11. 5 vs. 68. 3 +/- 20. 9 years, p = 0. 007). Low serum albumin (
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Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | diffuse idiopathic skeletal hyperostosis |
| disease | MESH | dysphagia |
| disease | MESH | osteophyte |
| drug | DRUGBANK | Human Serum Albumin |