Factors associated with asthma attack recurrence in Ecuadorian children: longitudinal study of potential impact of the COVID-19 pandemic lockdown.

Factors associated with asthma attack recurrence in Ecuadorian children: longitudinal study of potential impact of the COVID-19 pandemic lockdown.

Publication date: Nov 27, 2025

The COVID-19 pandemic caused a major disruption in access to and use of health resources and facilities. There are limited longitudinal data from low-resource settings on the impact of pandemic mitigation strategies and medication use on asthma attacks in children. We did a longitudinal study of risk factors for asthma attack recurrence among children aged 5-17 years presenting with an attack to emergency rooms in public hospitals in Ecuador. Children were followed for at least 12 months by monthly telemonitoring. Cox regression models for multiple recurrences were used to identify potential risk factors. 213 asthmatic children were recruited from May 2019 to March 2020 when recruitment was interrupted by a COVID-19 lockdown: 97% were followed for at least 12 months (median 419 days, IQRs 393-421 days). In multivariable analysis, the lockdown effect (adjusted HR 0. 35, 95% CI 0. 22 to 0. 56, p

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Concepts Keywords
Ecuador Adolescent
Hospitals Adrenal Cortex Hormones
Iqrs Adrenal Cortex Hormones
Monthly Asthma
Pandemic Asthma Epidemiology
Child
Child, Preschool
COVID-19
Ecuador
Female
Humans
Longitudinal Studies
Male
Paediatric asthma
Pandemics
Recurrence
Risk Factors
SARS-CoV-2

Semantics

Type Source Name
disease MESH asthma
pathway KEGG Asthma
disease MESH recurrence
disease MESH COVID-19 pandemic
disease MESH emergency

Original Article

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