Predictors of depressive symptoms and depression in women with previous pregnancy loss.

Publication date: Jun 01, 2026

Depressive symptoms are common in females after pregnancy loss. However, research on risk factors for developing a clinical depressive episode remains limited and with inconsistent findings. This study examined the association of demographic variables (like age), pregnancy-related factors (like number of miscarriages or stillbirths), clinical factors (like medical explanation for the pregnancy loss) and neuroticism (as a well-known risk factor for internalizing disorders) with a current major depressive episode and depression severity in 172 women with miscarriage or stillbirth within the previous year. Case-control study. Measures included the semi-structured diagnostic interview DIPS, the State-Trait Anxiety-Depression Inventory (STADI), the Short Version of the Big-Five Inventory (BFI-K). To identify predictors of depression, linear and logistic regression analyses were conducted. Lower medical support (p = . 041), higher stress immediately after the pregnancy loss (p = . 027) and higher neuroticism scores (p = . 008) were significant predictors of a current major depressive episode in woman with pregnancy loss. Incoherent farewell (p = . 043), a history of psychotherapy or psychiatric treatment in the last year (p = . 016) and higher neuroticism scores (p 

Concepts Keywords
Females Abortion, Spontaneous
Miscarriage Adult
Psychotherapy Anxiety Disorders
Stillbirths Case-Control Studies
Depression
depression
depressive symptoms
Female
Humans
Major Depressive Disorder
miscarriage
Neuroticism
predictors
Pregnancy
pregnancy loss
Risk Factors
Stillbirth
stillbirth
Young Adult

Semantics

Type Source Name
disease MESH miscarriages
disease MESH stillbirths
disease MESH included
disease MESH Anxiety
disease MESH Major Depressive Disorder

Original Article

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