Publication date: Jul 06, 2026
Autism spectrum disorder (ASD) is commonly associated with gastrointestinal comorbidities, particularly chronic constipation. Despite high clinical burden and frequent tertiary referrals, comparative data describing clinical characteristics, management and outcomes between children with and without ASD-and across ASD severity levels-remain limited. This study compared constipation outcomes at 1 year and the most recent follow-up between children with and without ASD and assessed whether autism severity influenced prognosis. We retrospectively analysed children with chronic constipation managed through a tertiary motility service and enrolled as of 31 January 2024. Demographics, comorbidities, adherence, interventions and outcomes were extracted. Subgroup analyses examined outcomes across ASD severity levels. Statistical comparisons used Chi-square, Mann-Whitney U and Kruskal-Wallis tests, with significance defined as p
| Concepts | Keywords |
|---|---|
| functional constipation | |
| treatment adherence | |
| “”” | |
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Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Constipation |
| disease | MESH | autism spectrum disorder |
| disease | MESH | autism |