Publication date: Jul 08, 2026
But the list of ailments the tuberculosis vaccine, also known as the Bacillus Calmette-GucE9rin (BCG) vaccine, could target doesn’t end there. Experts believe the vaccine may train the brain’s immune system, although this has not been studied before. However, children were not included in this study, so the vaccine’s effects on Alzheimer’s prevention observed here are limited to adults aged 55 years and older. In various previous studies, administration of the vaccine was associated with a reduced risk of Alzheimer’s disease and related dementias. In addition to ongoing studies on type 1 diabetes and COVID-19, the BCG vaccine has also been linked to Alzheimer’s disease. Over the past 100 years, the tuberculosis vaccine has been administered, and doctors have documented other benefits that came with its application. These benefits are called -off-target” effects and, in the case of the BCG vaccine, have been studied by researchers at Mass General Brigham over the last 20 years.
| Concepts | Keywords |
|---|---|
| Africa | Alzheimer |
| Cancer | Bcg |
| Diabetes | Brain |
| Neuroscience | Brigham |
| Vaccination | General |
| Immune | |
| Mass | |
| Participants | |
| Prevent | |
| Showed | |
| System | |
| Tuberculosis | |
| Vaccine | |
| Years |
Semantics
| Type | Source | Name |
|---|---|---|
| pathway | REACTOME | Immune System |