Burden and severe outcomes of influenza in comparison to COVID-19 among hospitalised adult patients during the 2024-2025 season: a prospective, multicentre study in Greece.

Publication date: Jul 21, 2026

To compare the burden and severe outcomes among patients hospitalised for influenza to those hospitalised for coronavirus disease 2019 (COVID-19) in Greece. The study was conducted in four hospitals from November 2024 to May 2025. Main outcomes were length of stay (LOS) and severe outcomes (admission to intensive care unit, invasive mechanical ventilation, in-hospital death). The associations between LOS and adverse outcomes with COVID-19 or influenza were estimated with multivariable negative binomial and logistic regression models. We studied 621 patients [mean age: 75. 6 years; 564 (90. 8%) with at least one comorbidity], of whom 43 (6. 9%) died. In total, 358 patients were admitted for COVID-19 and 263 for influenza. Influenza patients had a mean LOS of 10. 7 days compared with 7. 5 days among COVID-19 patients (p-value

Concepts Keywords
COVID-19
hospitalised patients
influenza
pneumonia
severe outcomes

Semantics

Type Source Name
disease MESH influenza
disease MESH COVID-19
disease MESH death
disease MESH Long Covid
disease MESH pneumonia

Original Article

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