Publication date: Jul 07, 2026
Long COVID affects about 6 in 100 people after a COVID-19 infection. It can cause ongoing problems like ongoing tiredness, muscle pain, and “brain fog. ” We know very little about which treatments might be helpful for long COVID. The goal of this trial is to compare two treatments for people with long COVID to try to manage their symptoms. The main question is to assess whether the Lightning Process is effective for people living with long COVID compared to activity pacing. Each person will be placed into one of the two groups randomly (by chance, like flipping a coin). Activity pacing helps people balance rest and daily activities. The Lightning Process teaches ways to change thought patterns and body responses to symptoms. We will include 100 adults with long COVID. Everything will be done online, including filling out surveys about health and daily life. The goal is to find out which approach helps people feel better and improve their daily activities.
| Concepts | Keywords |
|---|---|
| activity pacing | |
| fatigue | |
| Lightning Process | |
| long COVID | |
| post-exertional malaise |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Fatigue |
| disease | MESH | Long COVID |
| disease | MESH | COVID-19 |
| disease | MESH | infection |
| disease | MESH | muscle pain |
| disease | MESH | brain fog |
| drug | DRUGBANK | Isoxaflutole |
| drug | DRUGBANK | Tropicamide |
| disease | MESH | anosmia |
| disease | MESH | Post-Intensive Care Syndrome |
| disease | MESH | lung injury |