Publication date: Jul 15, 2026
Antimicrobial use among children in Japan has declined substantially; however, tetracycline use has increased among adolescents, particularly after 2017 and during the COVID-19 period, and the underlying clinical indications remain unclear. We aimed to characterize long-term trends in oral tetracycline use, changes in clinical indications, and treatment patterns among individuals aged
| Concepts | Keywords |
|---|---|
| acne vulgaris | |
| adolescents | |
| antimicrobial stewardship | |
| claims database | |
| tetracycline |
Semantics
| Type | Source | Name |
|---|---|---|
| drug | DRUGBANK | Tetracycline |
| disease | MESH | COVID-19 |
| disease | MESH | acne vulgaris |
Original Article
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