Publication date: Aug 01, 2026
In this study, we evaluated temporal changes in antimicrobial resistance (AMR) before, during and after the COVID-19 pandemic in Mexico. We conducted a multicentre, retrospective surveillance study that included clinically significant isolates of Gram-positive and Gram-negative bacteria collected across Mexico between January 2019 and December 2024. Differences in antibiotic resistance among clinical specimen types and across pre-pandemic, pandemic and post-pandemic periods were assessed using Fisher’s exact test and linear regression, as appropriate. A total of 156 193 isolates were analysed. Among Enterobacterales, extended-spectrum β-lactamase-producing Escherichia coli increased from the pre-pandemic to post-pandemic period (46. 5%-48. 9%, P for trend = 0. 005). Also, resistance to ertapenem (2. 0% to 3. 2%) and meropenem (1. 2% to 2. 7%) increased significantly (both P for trend
| Concepts | Keywords |
|---|---|
| Antibiotic | |
| Covid | |
| Evaluated | |
| Gram | |
| Increased | |
| Invifar | |
| Isolates | |
| Mexico | |
| Network | |
| Pandemic | |
| Post | |
| Pre | |
| Resistance | |
| Shift | |
| Study |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | COVID-19 pandemic |
| disease | MESH | included |
| drug | DRUGBANK | Ertapenem |
| drug | DRUGBANK | Meropenem |