Publication date: Oct 30, 2019 Clinical trials have demonstrated the efficacy of indigo naturalis, a traditional Chinese medicine ingredient, against psoriasis, a skin disease characterized by keratinocyte hyperproliferation and inflammation. ... Read more

Publication date: Oct 24, 2019 Skin cancer is one of the most common cancers worldwide. Melanoma accounts for ~5% of skin cancers but causes the large majority of skin cancer-related ... Read more

Publication date: Oct 28, 2019 Inefficient T-cell access to the tumor microenvironment (TME) is among the causes of tumor immune-resistance. Previous evidence demonstrated that targeting CXCR4 improves anti-PD-1/PD-L1 efficacy reshaping ... Read more

Publication date: Oct 14, 2019 Melanoma cells can switch between distinct gene expression profiles, resulting in “proliferative” and “invasive” phenotypes. Signaling pathways involved in this switch were analyzed by gene ... Read more

Publication date: Oct 14, 2019 Melanoma cells can switch between distinct gene expression profiles, resulting in “proliferative” and “invasive” phenotypes. Signaling pathways involved in this switch were analyzed by gene ... Read more

Publication date: Sep 24, 2019 NRAS mutations are the most common alterations among RAS isoforms in cutaneous melanoma, with patients harboring these aggressive tumors having a poor prognosis and low ... Read more

Publication date: Sep 05, 2019 Tobramycin is an aminoglycoside-based natural antibiotic derived from Streptomyces tenebrarius, which is primarily used for Gram-negative bacterial infection treatment. Although tobramycin has been utilized in ... Read more

Publication date: Feb 20, 2019 Neoplastic cells promote a hypercoagulable state by the expression of cell surface proteins, such as tissue factor. In BRAF mutated melanoma patients upon BRAF inhibitors, ... Read more

Publication date: Aug 28, 2019 In Korea and China, asiasari radix (AR) is widely used as a traditional anti-inflammatory and analgesic agent. After its skin-regenerating and hair loss-preventing activities were ... Read more

Publication date: Aug 27, 2019 We screen ion channels and transporters throughout the genome to identify those required by human melanoma cells but not by normal human melanocytes. We discover ... Read more