Search Results for: Alpha-1-proteinase inhibitor

November 11, 2024November 11, 2024

Cutaneous Melanoma: An Overview of Physiological and Therapeutic Aspects and Biotechnological Use of Serine Protease Inhibitors.

Melanoma Literature

Publication date: Aug 16, 2024 Metastatic melanoma stands out as the most lethal form of skin cancer because of its high propensity to spread and its remarkable resistance to treatment ... Read more

January 18, 2025January 18, 2025

Emotional distress and affective knowledge representation one year after the COVID-19 outbreak.

Coronavirus Literature

Publication date: Jan 17, 2025 This study examines whether the detrimental effects of the COVID-19 pandemic on the affectivity of the population extend one year after the outbreak. In an ... Read more

January 18, 2025January 18, 2025

Explainable Predictive Model for Suicidal Ideation During COVID-19: Social Media Discourse Study.

Coronavirus Literature

Publication date: Jan 17, 2025 Studying the impact of COVID-19 on mental health is both compelling and imperative for the health care system’s preparedness development. Discovering how pandemic conditions and ... Read more

January 17, 2025January 17, 2025

Active learning driven prioritisation of compounds from on-demand libraries targeting the SARS-CoV-2 main protease.

Coronavirus Literature

Publication date: Jan 08, 2025 FEgrow is an open-source software package for building congeneric series of compounds in protein binding pockets. For a given ligand core and receptor structure, it ... Read more

January 17, 2025January 17, 2025

Build a RAG-based scientific ChatBot with LangChain, Streamlit & PubMed – Part 2 (LLM-aided retrieval of scientific abstracts via PubMed API using natural language)

Dr. Richard A. Blevins News, Informatics News

Publication date: Jan 17, 2025 “””if simplify_query:self. logger. info(f’Trying to simplify scientist query {query}’)query_simplified = self. _simplify_pubmed_query(query)if query_simplified != query:self. logger. info(f’Initial query simplified to: {query_simplified}’)query = query_simplifiedelse:self. logger. info(‘Initial ... Read more

January 16, 2025January 16, 2025

Enhanced Large Language Models for Effective Screening of Depression and Anxiety

Major Depressive Disorder News

Publication date: Jan 15, 2025 Depressive and anxiety disorders are widespread, necessitating timely identification and management. Recent advances in Large Language Models (LLMs) offer potential solutions, yet high costs and ... Read more

January 15, 2025January 15, 2025

Fragmenstein: predicting protein-ligand structures of compounds derived from known crystallographic fragment hits using a strict conserved-binding-based methodology.

Coronavirus Literature

Publication date: Jan 13, 2025 Current strategies centred on either merging or linking initial hits from fragment-based drug design (FBDD) crystallographic screens generally do not fully leaverage 3D structural information. ... Read more

January 15, 2025January 15, 2025

Asymptomatic lung abscess of aspergillus in a female without previous lung diseases or immunocompromise: a case report.

Tuberculosis Literature

Publication date: Jan 14, 2025 Chronic pulmonary abscess usually results from bacterial or mycobacterium infection, but rarely from aspergillosis. Chronic pulmonary aspergillosis is usually found in a person with structural ... Read more

January 15, 2025January 15, 2025

Large Language Models: New Opportunities for Access to Science

Dr. Richard A. Blevins News, Informatics News

Publication date: Jan 13, 2025 The adaptation of Large Language Models like ChatGPT for information retrieval from scientific data, software and publications is offering new opportunities to simplify access to ... Read more

January 15, 2025January 15, 2025

Building a Simple Multi-Agent Platform Using Llama and LangGraph: A Hands-On Guide to Smarter Query Routing.

Dr. Richard A. Blevins News, Informatics News

Publication date: Jan 15, 2025 Vector Store Retrieval Agent Google Search Agent Wikipedia Search AgentRetrieval LayerIn this layer, you can see there are main 4 agents working together to get ... Read more