Search Results for: Asthma

January 17, 2020

Omics for the future in asthma.

Publication date: Jan 15, 2020 Asthma is a common, complex, multifaceted disease. It comprises multiple phenotypes, which might benefit from treatment with different types of innovative targeted therapies. Refining these ... Read more

January 10, 2020January 10, 2020

Are We meeting the Promise of Endotypes and Precision Medicine in Asthma.

Precision Medicine Literature

Publication date: Jan 09, 2020 While the term “asthma” has long been known to describe heterogeneous groupings of patients, only recently have data evolved which enable a molecular understanding of ... Read more

January 10, 2020January 10, 2020

Are We meeting the Promise of Endotypes and Precision Medicine in Asthma.

Precision Medicine Literature

January 5, 2020

Evolving phenotypes to endotypes: is precision medicine achievable in asthma?

Precision Medicine Literature

Publication date: Jan 03, 2020 Introduction: The development of biologic molecules led to a drastic change in the therapeutic approach to asthma. With the prospect of acting on different pathophysiological ... Read more

March 25, 2020March 25, 2020

Blinded sample size reestimation for negative binomial regression with baseline adjustment.

Multiple Sclerosis Literature

Publication date: Mar 23, 2020 In randomized clinical trials, it is standard to include baseline variables in the primary analysis as covariates, as it is recommended by international guidelines. For ... Read more

March 22, 2020

Adjunct low-dose ketamine infusion vs standard of care in mechanically ventilated critically ill patients at a Tertiary Saudi Hospital (ATTAINMENT Trial): study protocol for a randomized, prospective, pilot, feasibility trial.

Opioids Literature

Publication date: Mar 20, 2020 A noticeable interest in ketamine infusion for sedation management has developed among critical care physicians for critically ill patients. The 2018 Pain, Agitation/sedation, Delirium, Immobility, ... Read more

March 21, 2020

The role of chemokines and chemokine receptors in multiple sclerosis.

Multiple Sclerosis Literature

Publication date: Mar 17, 2020 Multiple sclerosis (MS) is a chronic inflammatory disease that is characterized by leukocyte infiltration and subsequent axonal damage, demyelinating inflammation, and formation of sclerosing plaques ... Read more

March 21, 2020March 21, 2020

The suppressive effect of dabrafenib, a therapeutic agent for metastatic melanoma, in IgE-mediated allergic inflammation.

Melanoma Literature

Publication date: Mar 17, 2020 The functional inhibition of mast cells, which serve as a key effector cells in allergic reactions may be a specific target for treating immunoglobulin (Ig)E-mediated ... Read more

March 19, 2020March 19, 2020

Robert O. Wright, MD, MPH: Precision Medicine and the Role of Exposomics

Precision Medicine Media

Publication date: Mar 18, 2020 “Precision Public Health, Precision Primary Care, and Precision Medicine: The Role of Exposomics” Robert O. Wright, MD, MPH, Professor and Ethel H. Wise Chair, Department ... Read more

March 19, 2020March 19, 2020

Robert O. Wright, MD, MPH: Precision Medicine and the Role of Exposomics

Precision Medicine Media