Search Results for: Axonal Growth

November 22, 2019November 22, 2019

NG2-glia cell proliferation and differentiation by glial growth factor 2 (GGF2), a strategy to promote functional recovery after ischemic stroke.

Melanoma Literature

Publication date: Nov 18, 2019 Stroke is the leading cause of adult disability. Spontaneous functional recovery occurs after ischemic stroke, but it is very limited. Therefore, it is urgent to ... Read more

March 1, 2019March 1, 2019

Axonal and Myelin Neuroprotection by the Peptoid BN201 in Brain Inflammation.

Multiple Sclerosis Literature

Publication date: Feb 27, 2019 The development of neuroprotective therapies is a sought-after goal. By screening combinatorial chemical libraries using in vitro assays, we identified the small molecule BN201 that ... Read more

February 8, 2019February 8, 2019

Excess active P13K rescues huntingtin-mediated neuronal cell death but has no effect on axonal transport defects.

Huntington's Disease Literature

Publication date: Feb 06, 2019 High levels of oxidative stress is detected in neurons affected by many neurodegenerative diseases, including huntington’s disease. Many of these diseases also show neuronal cell ... Read more

February 8, 2019February 8, 2019

Excess active P13K rescues huntingtin-mediated neuronal cell death but has no effect on axonal transport defects.

Huntington's Disease Literature

December 6, 2019

Circulating Brain-enriched MicroRNAs for detection and discrimination of idiopathic and genetic Parkinson’s disease.

Parkinson's Disease Literature

Publication date: Dec 04, 2019 A minimally invasive test for early detection and monitoring of Parkinson’s disease (PD) is a highly unmet need for drug development and planning of patient ... Read more

September 1, 2019September 1, 2019

The potential of memory enhancement through modulation of perineuronal nets.

Precision Medicine Literature

Publication date: Sep 01, 2019 With an increasingly aging global population, the incidence of neurological diseases such as dementia is set to increase to unmanageable levels, yet there are currently ... Read more

July 10, 2019July 10, 2019

Study of BDNF Pathway Biomarkers in the Cerebrospinal Fluid in Patients With Huntington’s Disease

Huntington's Disease News

Publication date: Jul 09, 2019 Huntington disease (HD, 1.3/10 000) is an autosomal dominant disease due to an abnormal expansion of CAG triplets in HTT gene. Several pathophysiological mechanisms have ... Read more

March 28, 2019March 28, 2019

Dysregulation of CRMP2 Post-Translational Modifications Drive Its Pathological Functions.

Multiple Sclerosis Literature

Publication date: Mar 27, 2019 Collapsin response mediator proteins (CRMPs) are a family of ubiquitously expressed, homologous phosphoproteins best known for coordinating cytoskeletal formation and regulating cellular division, migration, polarity, ... Read more

August 11, 2018August 11, 2018

Cerebrospinal fluid GAP-43 in early multiple sclerosis.

Multiple Sclerosis Literature

Publication date: Jan 21, 2018 Novel biomarkers identifying and predicting disease activity in multiple sclerosis (MS) would be valuable for primary diagnosis and as outcome measures for monitoring therapeutic effects ... Read more

February 21, 2018February 21, 2018

Cerebrospinal fluid level of Nogo receptor 1 antagonist lateral olfactory tract usher substance (LOTUS) correlates inversely with the extent of neuroinflammation.

Multiple Sclerosis Literature

Publication date: Feb 17, 2018 Although inflammation in the central nervous system is responsible for multiple neurological diseases, the lack of appropriate biomarkers makes it difficult to evaluate inflammatory activities ... Read more