Search Results for: Based

June 12, 2025

Mediation Effects of Sleep Efficiency and Total Sleep Time of PSG and Apathy in Cognitively Unimpaired Older Adults With Childhood Trauma: A Community-Based Study.

Publication date: Aug 01, 2025 Childhood trauma is linked to sleep quality and mental health in adults. However, there is limited research exploring their connections in older adults. We aimed ... Read more

June 12, 2025

A one-pot assay based on PAM-free recombinase polymerase amplification and CRISPR/Cas12a for rapid detection of SARS-CoV-2 N gene.

Coronavirus Literature

Publication date: Jun 09, 2025 SARS-CoV-2 is a pathogenic virus, which exhibits high contagiousness. Therefore, a rapid and sensitive SARS-CoV-2 detection strategy is imperative. Herein, a one-pot assay by the ... Read more

June 12, 2025June 12, 2025

Experiences of Individually Tailored Internet-Based Cognitive Behavioral Therapy During the COVID-19 Pandemic: Qualitative Interview Study.

Coronavirus Literature

Publication date: Jun 11, 2025 During the COVID-19 pandemic, both physical and psychological health were at risk. Internet-based cognitive behavioral therapy (ICBT) is a psychological treatment alternative that does not ... Read more

June 12, 2025

Research Electronic Data Capture (REDCap) for Population-Based Data Collection in Low- and Middle-Income Countries: Opportunities, Challenges, and Solutions.

Coronavirus Literature

Publication date: Jun 11, 2025 Health research requires high-quality data, and population-based health research comes with specific opportunities and challenges for data collection. Electronic data capture can mitigate some of ... Read more

June 12, 2025

Risk of tuberculosis in individuals with type 2 diabetes mellitus based on the tuberculosis predictive index score: a case-control study in Indonesia.

Tuberculosis Literature

Publication date: Jun 11, 2025 The co-occurrence of tuberculosis (TB) and diabetes mellitus presents a significant global health challenge, marked by a bidirectional relationship. This study aims to evaluate the ... Read more

June 12, 2025

Characterization of DnaB-DnaG Interaction in M. tuberculosis using a SAXS-Based Dissociation Assay.

Tuberculosis Literature

Publication date: Jun 11, 2025 We studied the complex interactions between helicase and primase, two key components of the replisome involved in DNA replication in Mycobacterium tuberculosis. Utilizing purified, complementary ... Read more

June 12, 2025

Enhancing Pulmonary Disease Prediction Using Large Language Models With Feature Summarization and Hybrid Retrieval-Augmented Generation: Multicenter Methodological Study Based on Radiology Report.

Tuberculosis Literature

Publication date: Jun 11, 2025 The rapid advancements in natural language processing, particularly the development of large language models (LLMs), have opened new avenues for managing complex clinical text data. ... Read more

June 11, 2025

ANKK1, ANKRD50, GRK5, PACSIN1 and VPS8 are novel candidate genes associated with late onset Parkinson’s disease: Definition of a novel predictive protocol based on polygenic model of inheritance.

Parkinson's Disease Literature

Publication date: Jun 08, 2025 Parkinson’s disease (PD) represents one of the most frequent neurodegenerative disorders for which genetic diagnosis is still challenging due to the high genetic heterogeneity associated ... Read more

June 11, 2025

Deep-learning-based Partial Volume Correction in 99mTc-TRODAT-1 SPECT for Parkinson’s Disease: A Preliminary Study on Clinical Translation.

Parkinson's Disease Literature

Publication date: Jun 10, 2025 Tc-TRODAT-1 SPECT is effective for the early detection of Parkinson’s disease (PD). However, SPECT images suffer from severe partial volume effect, which impairs tissue boundary ... Read more

June 11, 2025

Effectiveness of Hospital Ambulance Utilization in a Community-Based Integrated Care System.

Coronavirus Literature

Publication date: May 01, 2025 Background and objectives In recent years, the number of emergency transports for older patients has significantly increased, raising concerns about the strain on emergency medical ... Read more