Search Results for: Blood

September 13, 2019September 13, 2019

Fatigue in Parkinson’s Disease Associates with Lower Ambulatory Diastolic Blood Pressure.

Publication date: Jun 04, 2019 Fatigue is a common debilitating symptom in Parkinson’s disease (PD) of unclear etiology. Hypotension and blood pressure variability are common in PD though their relationship ... Read more

September 13, 2019

A computational approach to identify blood cell-expressed Parkinson’s disease biomarkers that are coordinately expressed in brain tissue.

Parkinson's Disease Literature

Publication date: Aug 09, 2019 Identification of genes whose regulation of expression is functionally similar in both brain tissue and blood cells could in principle enable monitoring of significant neurological ... Read more

August 31, 2019August 31, 2019

Improved drug delivery to brain metastases by peptide-mediated permeabilization of the blood-brain barrier.

Melanoma Literature

Publication date: Aug 29, 2019 Melanoma patients have a high risk of developing brain metastasis, which is associated with a dismal prognosis. During early stages of metastasis development, the blood-brain ... Read more

August 22, 2019August 22, 2019

YOUR HEALTH: A key blood test that could better detect Parkinson’s

Parkinson's Disease News

Publication date: Aug 22, 2019 “Dopamine measurement plays an important role for people suffering from Parkinson’s,” a professor at the University of Central Florida. So Professor Chanda and his team ... Read more

August 8, 2019August 8, 2019

What human blood-brain barrier models can tell us about BBB function and drug discovery?

Huntington's Disease Literature

Publication date: Aug 06, 2019 Introduction: Human in vitro blood-brain barrier (BBB) models could be important tools for studying BBB development, maintenance and regulation. However, our capacity to obtain information ... Read more

July 26, 2019July 26, 2019

Clonality of CD4 Blood T Cells Predicts Longer Survival With CTLA4 or PD-1 Checkpoint Inhibition in Advanced Melanoma.

Melanoma Literature

Publication date: Mar 04, 2019 Recognition of cancer antigens drives the clonal expansion of cancer-reactive T cells, which is thought to contribute to restricted T-cell receptor (TCR) repertoires in tumor-infiltrating ... Read more

July 26, 2019July 26, 2019

Cerebral Blood Flow and tDCS

Multiple Sclerosis News

Publication date: Jul 25, 2019 With this study, the investigators will substantiate if regional cerebral blood flow (CBF) is affected by tDCS, assess the amount of CBF change in relation ... Read more

July 23, 2019July 23, 2019

Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals.

Precision Medicine Literature

Publication date: Jul 22, 2019 Selection of antihypertensive treatment according to self-defined ethnicity is recommended by some guidelines but might be better guided by individual genotype rather than ethnicity or ... Read more

July 18, 2019July 18, 2019

The HLA-DRB1 risk alleles for multiple sclerosis are differentially expressed in blood cells of patients from Southern Italy.

Multiple Sclerosis Literature

Publication date: Jul 17, 2019 HLA gene expression has an important role in the autoimmune disease predisposition. We investigated the mRNA expression profile of the risk alleles HLA-DRB1*15 and HLA-DRB1*13 ... Read more

July 14, 2019July 14, 2019

Breakdown of the blood-eye barrier in choroidal melanoma after proton beam radiotherapy.

Melanoma Literature

Publication date: Jul 12, 2019 Irradiation of choroidal melanoma is a safe and globe preserving procedure. Chronic inflammatory processes and ischemia are the main reasons for secondary enucleation in the ... Read more