Search Results for: Brain

April 21, 2025

Perineuronal Nets: Role in Normal Brain Physiology and Aging, and Pathology of various Diseases.

Publication date: Apr 18, 2025 Perineuronal nets (PNNs) are a specialized extracellular matrix in the central nervous system. They are widely distributed in the brain, with distribution patterns varying by ... Read more

April 21, 2025

Shared Mechanisms of Blood-Brain Barrier Dysfunction and Neuroinflammation in COVID-19 and Alzheimer’s Disease.

Coronavirus Literature

Publication date: Apr 18, 2025 The COVID-19 pandemic, caused by SARS-CoV-2, has highlighted the virus’s impact on the central nervous system (CNS) and its potential to exacerbate neurodegenerative diseases like ... Read more

April 21, 2025

Abnormal brain activation in autism spectrum disorder during negative emotion processing: A meta-analysis of functional neuroimaging studies.

Autism Literature

Publication date: May 01, 2025 Autism Spectrum Disorder (ASD) has deficits in emotional processing, which is one of the most common abnormalities in ASD social skills. Studies have shown that ... Read more

April 21, 2025

The Genetic and Phenotypic Spectrum of Primary Brain Calcification in a Large Cohort from China.

Parkinson's Disease Literature

Publication date: Apr 19, 2025 Primary brain calcification (PBC) is a monogenic inherited disease characterized by calcifications in basal ganglia and other brain regions, with seven causative genes identified and ... Read more

April 21, 2025

Deep brain stimulation alleviates Parkinsonian motor deficits through desynchronizing GABA release in mice.

Parkinson's Disease Literature

Publication date: Apr 19, 2025 High-frequency deep brain stimulation (DBS) at subthalamic nucleus (STN) is an effective therapy for Parkinson’s disease (PD), but the underlying mechanisms remain unclear. Here we ... Read more

April 21, 2025April 21, 2025

Investigating the relationship between sleep disturbances and cortical thickness, brainstem volume, amyloid accumulation, and inflammatory markers in Parkinson’s disease patients.

Parkinson's Disease Literature

Publication date: Apr 17, 2025 This study aimed to explore the relationship between self-reported sleep disturbances (e. g., insomnia, REM sleep behavior disorder ) and cortical thickness, brainstem volume, amyloid ... Read more

April 21, 2025

Are we ready for automated deep brain stimulation programming?

Parkinson's Disease Literature

Publication date: May 01, 2025 Deep brain stimulation (DBS) requires individualized programming of stimulation parameters, a time-consuming process performed manually by clinicians with specialized training. This process limits DBS accessibility, ... Read more

April 21, 2025April 21, 2025

Local connections enhancement as a neuroprotective strategy against depression recurrence: Insights from structural brain network analysis.

Major Depressive Disorder Literature

Publication date: May 01, 2025 Depression recurrence significantly impacts patients’ well-being and presents a major clinical challenge. Identifying the risk of recurrence during remission could enable early intervention and prevent ... Read more

April 21, 2025

Acute ivermectin toxicity on skin and brain tissue of adult albino rats: Evaluation of the role of Flumazenil and Vitamin C as new treatment modalities.

Coronavirus Literature

Publication date: Jun 01, 2025 Ivermectin, a natural antiviral drug, has been recommended for treating various diseases, including Coronavirus Disease 2019. This study aimed to evaluate the potential histopathological and ... Read more

April 20, 2025April 20, 2025

Neurological Impact of SARS-CoV-2 Changing Variants: A 4-Year DW-MRI Study on Olfactory and Taste-Related Brain Regions.

Coronavirus Literature

Publication date: Mar 29, 2025 Neurological symptoms such as impaired smell and taste have been recognized as hallmark manifestations of severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection. This study investigates ... Read more