Search Results for: Brain Metastases

June 1, 2023June 1, 2023

Efficacy of neoadjuvant stereotactic radiotherapy in brain metastases from solid cancer: a systematic review of literature and meta-analysis.

Melanoma Literature

Publication date: May 31, 2023 Neoadjuvant stereotactic radiotherapy (NaSRT) is a novel strategy for brain metastasis (BM) treatment, promising to achieve good local control, improved survival, and low toxicity. This ... Read more

June 1, 2023June 1, 2023

Gene-edited and -engineered stem cell platform drives immunotherapy for brain metastatic melanomas.

Melanoma Literature

Publication date: May 31, 2023 Oncolytic virus therapy has shown activity against primary melanomas; however, its efficacy in brain metastases remains challenging, mainly because of the delivery and immunosuppressive nature ... Read more

June 1, 2023June 1, 2023

Gene engineered cell therapy developed to target brain metastatic melanomas

Melanoma News

Publication date: May 30, 2023 Notably, the authors were able to design a preclinical mouse model that faithfully represents a human model of melanoma with leptomeningeal metastasis, which they used ... Read more

May 29, 2023May 29, 2023

Characteristics and outcomes of advanced melanoma patients with complete response and elective discontinuation of first-line anti-programmed death-1 monotherapy: A real-world multicentre observational cohort study.

Melanoma Literature

Publication date: May 27, 2023 Anti-programmed death-1 (anti-PD1) treatment has significantly improved outcomes of advanced melanoma with a considerable percentage of patients achieving complete response (CR). This real-world study analyzed ... Read more