Search Results for: Calcium

January 9, 2025January 9, 2025

Calcium-Binding Proteins in the Autistic Brain-Potential Links to Symptom Development.

Autism Literature

Publication date: Feb 01, 2025 Autism spectrum disorder (ASD) is a complex challenge, influenced by genetic and environmental factors. This review focuses on the proteins calbindin (CB), calretinin (CR) and ... Read more

December 25, 2024December 25, 2024

Co-Delivery of aPD-L1 and CD73 Inhibitor Using Calcium Phosphate Nanoparticles for Enhanced Melanoma Immunotherapy with Reduced Toxicity.

Melanoma Literature

Publication date: Dec 24, 2024 Melanoma, a malignant skin tumor, presents significant treatment challenges, particularly in unresectable and metastatic cases. While immune checkpoint inhibitors (ICIs) targeting PD-1/PD-L1 have brought new ... Read more

December 4, 2024December 4, 2024

Electrospun nanofibrous scaffolds reinforced with therapeutic lithium/manganese-doped calcium phosphates: Advancing skin cancer therapy through apoptosis induction.

Melanoma Literature

Publication date: Jan 01, 2025 In the current study we fabricated potent materials by incorporating therapeutic elements into calcium phosphates (CPs) to combat cancer. This involved synthesizing manganese (Mn)- and ... Read more

November 30, 2024November 30, 2024

TMBIM6/BI-1 is an intracellular environmental regulator that induces paraptosis in cancer via ROS and Calcium-activated ERAD II pathways.

Parkinson's Disease Literature

Publication date: Nov 29, 2024 Transmembrane B cell lymphoma 2-associated X protein inhibitor motif-containing (TMBIM) 6, also known as Bax Inhibitor-1 (BI-1), has been heavily researched for its cytoprotective functions. ... Read more

November 29, 2024November 29, 2024

Oncogenic GNAQ/11-induced remodeling of the IP3/Calcium signaling pathway protects Uveal Melanoma against Calcium-driven cell death

Melanoma News

Publication date: Nov 27, 2024 Despite being considered a rare tumor, uveal melanoma (UVM) is the most common adult intraocular malignancy. With a poor prognosis and limited treatment options, up ... Read more

November 17, 2024November 17, 2024

Cannabinoid regulation of angiotensin II-induced calcium signaling in striatal neurons.

Parkinson's Disease Literature

Publication date: Nov 15, 2024 Calcium ion (Ca) homeostasis is crucial for neuron function and neurotransmission. This study focused on the actions mediated by the CB receptor (CBR), the most ... Read more

November 15, 2024November 15, 2024

Calcium signaling from damaged lysosomes induces cytoprotective stress granules.

Coronavirus Literature

Publication date: Nov 12, 2024 Lysosomal damage induces stress granule (SG) formation. However, the importance of SGs in determining cell fate and the precise mechanisms that mediate SG formation in ... Read more

November 15, 2024November 15, 2024

Calcium signaling from damaged lysosomes induces cytoprotective stress granules.

Coronavirus Literature

November 15, 2024November 15, 2024

Calcium signaling from damaged lysosomes induces cytoprotective stress granules.

Coronavirus Literature

November 15, 2024November 15, 2024

Calcium signaling from damaged lysosomes induces cytoprotective stress granules.

Coronavirus Literature