Search Results for: Carboxyamidotriazole

March 23, 2025March 23, 2025

A novel replicase-mediated self-amplifying RNA amplification mechanism of the SARS-CoV-2 replication-transcription system.

Publication date: Mar 18, 2025 A novel self-amplifying mRNA (samRNA) amplification mechanism was first discovered in the SARS-CoV-2 replication-transcription system and named replicase cycling reaction (RCR). In principle, RCR is ... Read more

March 23, 2025March 23, 2025

A novel approach to forecasting reproduction numbers of spatiotemporal stochastic epidemic spread using a PDE-based model and real-time infection data.

Coronavirus Literature

Publication date: Mar 21, 2025 The COVID-19 pandemic highlighted the need for improved epidemic spread forecasting, a critical precursor for developing optimal control measures for spread mitigation. Well-recognized shortcomings in ... Read more

March 22, 2025March 22, 2025

Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines.

Melanoma Literature

Publication date: Mar 20, 2025 Personalized cancer vaccines (PCVs) largely leverage neoantigens arising from somatic mutations, limiting their application to patients with relatively high tumor mutational burden (TMB). This underscores ... Read more

March 22, 2025March 22, 2025

Evolution characteristics and obstacle factors of rural resilience in Chinese minority areas in the background of rural tourism and COVID-19.

Coronavirus Literature

Publication date: Mar 19, 2025 Rural tourism and COVID-19 have brought significant impacts and lasting challenges to the resilience development of rural territorial systems. To improve the livelihoods of farmers ... Read more

March 22, 2025March 22, 2025

Evolution characteristics and obstacle factors of rural resilience in Chinese minority areas in the background of rural tourism and COVID-19.

Coronavirus Literature

March 20, 2025March 20, 2025

Identifying behavior regulatory leverage over mental disorders transcriptomic network hubs toward lifestyle-dependent psychiatric drugs repurposing.

Major Depressive Disorder Literature

Publication date: Mar 19, 2025 There is a vast prevalence of mental disorders, but patient responses to psychiatric medication fluctuate. As food choices and daily habits play a fundamental role ... Read more

March 20, 2025March 20, 2025

Discovery of a novel Betacoronavirus 1, cpCoV, in goats in China: The new risk of cross-species transmission.

Coronavirus Literature

Publication date: Mar 01, 2025 Betacoronavirus is a causative agent of respiratory and enteric diseases in humans and animals. Several ruminants are recognized to be intermediate hosts in the transmission ... Read more

March 20, 2025March 20, 2025

Discovery of a novel Betacoronavirus 1, cpCoV, in goats in China: The new risk of cross-species transmission.

Coronavirus Literature

March 20, 2025March 20, 2025

Factors shaping the mental health of healthcare workers during the COVID-19 pandemic: a qualitative study in Ghana.

Coronavirus Literature

Publication date: Mar 17, 2025 The COVID-19 pandemic negatively impacted the working conditions and mental health of healthcare workers (HCWs) across the globe. Little is understood of the factors influencing ... Read more

March 20, 2025March 20, 2025

Factors shaping the mental health of healthcare workers during the COVID-19 pandemic: a qualitative study in Ghana.

Coronavirus Literature