Search Results for: Chinese

June 8, 2019June 8, 2019

Misassembly of long reads undermines de novo-assembled ethnicity-specific genomes: validation in a Chinese Han population.

Publication date: Jun 05, 2019 An ethnicity is characterized by genomic fragments, single nucleotide polymorphisms (SNPs), and structural variations specific to it. However, the widely used ‘standard human reference genome’ ... Read more

June 1, 2019June 1, 2019

Deep generative learning for automated EHR diagnosis of traditional Chinese medicine.

Precision Medicine Literature

Publication date: Jun 01, 2019 Computer-aided medical decision-making (CAMDM) is the method to utilize massive EMR data as both empirical and evidence support for the decision procedure of healthcare activities. ... Read more

May 21, 2019May 21, 2019

Gut dysbiosis and lack of short chain fatty acids in a Chinese cohort of patients with multiple sclerosis.

Multiple Sclerosis Literature

Publication date: May 17, 2019 Recent studies, mostly conducted in Western countries, showed that gut microbes are involved in the pathogenesis of multiple sclerosis (MS). The aim of this study ... Read more

April 14, 2019April 14, 2019

A Phase Ib Study of Pembrolizumab as Second-Line Therapy for Chinese Patients With Advanced or Metastatic Melanoma (KEYNOTE-151).

Melanoma Literature

Publication date: Apr 09, 2019 Pembrolizumab shows robust antitumor activity and favorable safety in metastatic melanoma. KEYNOTE-151 evaluated pembrolizumab in Chinese patients, who have more aggressive melanoma subtypes than other ... Read more

April 14, 2019April 14, 2019

A Phase Ib Study of Pembrolizumab as Second-Line Therapy for Chinese Patients With Advanced or Metastatic Melanoma (KEYNOTE-151).

Melanoma Literature

April 10, 2019

Attention-based deep residual learning network for entity relation extraction in Chinese EMRs.

Precision Medicine Literature

Publication date: Apr 09, 2019 Electronic medical records (EMRs) contain a variety of valuable medical concepts and relations. The ability to recognize relations between medical concepts described in EMRs enables ... Read more

April 1, 2019April 1, 2019

Interferon-α versus interleukin-2 in Chinese patients with malignant melanoma: a randomized, controlled, trial.

Melanoma Literature

Publication date: Apr 01, 2019 The US Food and Drug Association has approved interferon-α (IFN-α) and interleukin-2 (IL-2) as adjuvant therapy in malignant melanoma. The objective of the study was ... Read more

March 20, 2019March 20, 2019

Effect of Apolipoprotein E Genotypes on Huntington’s Disease Phenotypes in a Han Chinese Population.

Huntington's Disease Literature

Publication date: Mar 18, 2019 Huntington’s disease (HD) is an autosomal dominant degenerative disease that mainly encompasses movement, cognition, and behavioral symptoms. The apolipoprotein E (APOE) gene is thought to ... Read more

February 6, 2019February 6, 2019

Concordance between the interictal focal EEG pattern and MRI lesions as a predictor of a favorable surgical outcome in patients with epileptic spasms: a Chinese study.

Multiple Sclerosis Literature

Publication date: Feb 01, 2019 OBJECTIVEThe aim of this study was to evaluate the electro-clinical features, etiology, treatment, and postsurgical seizure outcomes in patients with intractable epileptic spasms (ESs).METHODSThe authors ... Read more

February 6, 2019February 6, 2019

Association of FAM65B, AGBL4, and CUX2 genetic polymorphisms with susceptibility to antituberculosis drug-induced hepatotoxicity: validation study in a Chinese Han population.

Tuberculosis Literature

Publication date: Feb 01, 2019 Antituberculosis (anti-TB) drug-induced hepatotoxicity (ATDH) is a serious adverse drug reaction, and its pathogenic mechanism has not been elucidated thoroughly to date. A recent genome-wide ... Read more