Search Results for: Chinese

March 18, 2020

MUC4 isoforms expression profiling and prognosis value in Chinese melanoma patients.

Melanoma Literature

Publication date: Mar 14, 2020 Mucin 4 (MUC4), a type I membrane-bound mucin, blocks apoptosis, promotes invasion, proliferation and migration and causes chemo-resistance in epithelial cancers. However, the expression profiling ... Read more

February 20, 2020February 20, 2020

Adjuvant pembrolizumab versus high-dose interferon α-2b for Chinese patients with resected stage III melanoma: a retrospective cohort study.

Melanoma Literature

Publication date: Feb 18, 2020 Background Pembrolizumab has robust antitumor activity in advanced melanoma and has been approved for the treatment of melanoma in many countries. Adjuvant pembrolizumab was associated ... Read more

February 20, 2020February 20, 2020

Variants in the Upstream Region of the Insulin Receptor Substrate-1 Gene Is Associated with Major Depressive Disorder in the Han Chinese Population

Major Depressive Disorder News

Publication date: Feb 19, 2020 Results: A haplotype in the 5ʹ-upstream region of IRS-1 consisting of rs13411764 and rs3820926 was a risk factor of MDD. Discussion: The findings imply that ... Read more

February 15, 2020

Responses to academic stress mediate the association between sleep difficulties and depressive/anxiety symptoms in Chinese adolescents.

Major Depressive Disorder Literature

Publication date: Feb 15, 2020 Sleep difficulties are pervasive in Chinese adolescents, which exert aversive influence on their emotional health. However, the underlying mechanisms of this effect remain unclear. This ... Read more

February 13, 2020February 13, 2020

Identification of TNFA influencing MDD risk and clinical features in Han Chinese.

Major Depressive Disorder Literature

Publication date: Feb 08, 2020 Our recent genetic-neuroimaging study observed that the rs1799724 polymorphism within the TNFA gene encoding TNF-? selectively affects the anatomy of visual cortex in patients with ... Read more

February 9, 2020February 9, 2020

Validating a targeted next-generation sequencing assay and profiling somatic variants in Chinese non-small cell lung cancer patients.

Precision Medicine Literature

Publication date: Feb 07, 2020 Non-small cell lung cancer (NSCLC) is featured with complex genomic alterations. Molecular profiling of large cohort of NSCLC patients is thus a prerequisite for precision ... Read more

December 21, 2019December 21, 2019

Heterogeneous information network based clustering for precision traditional Chinese medicine.

Precision Medicine Literature

Publication date: Dec 19, 2019 Traditional Chinese medicine (TCM) is a highly important complement to modern medicine and is widely practiced in China and in many other countries. The work ... Read more

March 22, 2020

Systemic Analysis of the Prognosis-Related RNA Alternative Splicing Signals in Melanoma.

Melanoma Literature

Publication date: Mar 21, 2020 BACKGROUND Alternative splicing (AS), the mechanism underlying the occurrence of protein diversity, may result in cancer genesis and development when it becomes out of control, ... Read more

March 22, 2020March 22, 2020

MPTP-Induced Impairment of Cardiovascular Function.

Parkinson's Disease Literature

Publication date: Mar 20, 2020 Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the accumulation of Lewy bodies and loss of dopaminergic neurons in the substantia nigra pars compacta ... Read more

March 20, 2020

Identification of CD200R1 promoter and the association of its polymorphisms with the risk of Parkinson’s disease.

Parkinson's Disease Literature

Publication date: Mar 19, 2020 Neuroinflammation is known to be involved in the pathogenesis of Parkinson’s disease (PD). Abnormal activation of microglia plays a key role in this pathological process. ... Read more