Search Results for: Clinical

May 21, 2025May 21, 2025

A clinical-dermoscopic risk scoring model for early melanoma of the soles: The iDScore_plantar.

Melanoma Literature

Publication date: May 20, 2025 Melanoma of the sole is an aggressive rare form, often diagnosed late. Plantar atypical nevi (pAN) are frequently misdiagnosed as plantar early melanomas (pEM) and ... Read more

May 21, 2025May 21, 2025

Preclinical evaluation of [At]At-AuNP-ABDMPL16 for targeted alpha therapy in Melanoma.

Melanoma Literature

Publication date: May 20, 2025 The aim of this study is to overcome the challenges of poor tumor penetration and systemic toxicity in targeted alpha therapy (TAT) while also evaluating ... Read more

May 21, 2025May 21, 2025

A retrospective analysis of vortioxetine utilization in children and adolescents with major depressive disorder in clinical practice.

Major Depressive Disorder Literature

Publication date: May 20, 2025 Treating depression in children and adolescents has always been a challenge in clinical pharmacotherapy. Vortioxetine, as a new type of antidepressant, is considered to have ... Read more

May 21, 2025May 21, 2025

Myopericardial complications following COVID-19 disease and vaccination: a clinical consensus statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases.

Coronavirus Literature

Publication date: May 20, 2025 The aim of the present clinical consensus statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases is to review the ... Read more

May 21, 2025May 21, 2025

Epidemiological and clinical profile of viral respiratory infections in children under 5 years at pre- and post-COVID-19 era in Praia, Cabo Verde.

Coronavirus Literature

Publication date: May 20, 2025 The coronavirus disease-19 (COVID-19) pandemic has affected global health, influencing the prevalence of different respiratory pathogens. The aim of this study is to evaluate the ... Read more

May 21, 2025

Age influences blood cell-based immune deregulation antibody response and unfavorable clinical outcomes in COVID-19 patients.

Coronavirus Literature

Publication date: May 20, 2025 COVID-19 is caused by SARS-CoV-2 and has a diverse spectrum of clinical presentations ranging from asymptomatic cases to severe and critical cases that result in ... Read more

May 20, 2025

Artificial Intelligence in Dermatology: A Comprehensive Review of Approved Applications, Clinical Implementation, and Future Directions.

Melanoma Literature

Publication date: May 19, 2025 This comprehensive review examines artificial intelligence (AI) applications in dermatology, approved by the United States (U. S.) Food and Drug Administration (FDA) and international organizations, ... Read more

May 20, 2025

Rationale and feasibility of a rapid integral biomarker program that informs immune-oncology clinical trials: the ADVISE trial.

Melanoma Literature

Publication date: May 19, 2025 ADVISE (ADaptiVe biomarker trial that InformS Evolution of therapy) (NCT03335540) was a biomarker-adapted feasibility clinical trial of immunohistochemistry (IHC) to inform combination immuno-oncology (I-O) treatment. ... Read more

May 20, 2025

Sex differences in 6-OHDA lesioned rats in a preclinical model for Parkinson’s disease.

Parkinson's Disease Literature

Publication date: May 17, 2025 Although Parkinson’s disease (PD) was first described in 1817, its etiology remains unclear. The primary neurotransmitter system affected in PD is the nigrostriatal dopaminergic pathway, ... Read more

May 20, 2025May 20, 2025

Parkinson’s Disease and glucose dysregulation: shared pathophysiological mechanisms and clinical implications.

Parkinson's Disease Literature

Publication date: May 19, 2025 The relationship between Parkinson’s Disease (PD) and type 2 diabetes mellitus (T2DM) is attracting increasing research interest. Epidemiological data shows a remarkable association between these ... Read more