Search Results for: Clinical

January 18, 2025January 18, 2025

Impact of the COVID-19 pandemic on epidemiological and clinical characteristics of inpatients with burns in a Northwest China burn centre: a retrospective study.

Publication date: Jan 15, 2025 This study aimed to assess the impact of the COVID-19 pandemic on the characteristics and outcomes of patients with burns in a burn centre situated ... Read more

January 18, 2025January 18, 2025

Predicting work ability impairment in post COVID-19 patients: a machine learning model based on clinical parameters.

Coronavirus Literature

Publication date: Jan 16, 2025 The Post COVID-19 condition (PCC) is a complex disease affecting health and everyday functioning. This is well reflected by a patient’s inability to work (ITW). ... Read more

January 18, 2025January 18, 2025

Beyond COVID-19: Reported clinical practices in maternity care in Victoria during the COVID-19 pandemic and implications for the future – A statewide review.

Coronavirus Literature

Publication date: Jan 16, 2025 In Australia, during the COVID-19 pandemic many routine pregnancy visits were replaced by telehealth, along with changes to routine screening and visitor policies. Many providers ... Read more

January 18, 2025January 18, 2025

Monocentric Study on the Clinical and Ultrasound Incidence of Rheumathologic Immune Related Adverse Events in Patients Affected by Stage IIB, IIC, III and IV Melanoma Under Therapy With Immune-checkpoint Inhibitors

Melanoma News

Publication date: Jan 13, 2025 Rheumatologic adverse events are expected to affect between 3% and 7. 5% of patients undergoing immunotherapy and are likely to be underdiagnosed. The main aim ... Read more

January 18, 2025January 18, 2025

A Prospective, Multicenter, Open-label, Randomized, Actively Controlled, Parallel-group Phase 3 Clinical Trial to Evaluate Efficacy, Safety, and Tolerability of IMA203 Versus Investigator’s Choice of Treatment in Patients With Previously Treated, Unresectable or Metastatic Cutaneous Melanoma (ACTengine® IMA203-301)

Melanoma News

Publication date: Jan 16, 2025 This clinical trial is a prospective, multicenter, open-label, randomized, actively controlled, parallel-group Phase 3 clinical trial to evaluate the efficacy, safety and tolerability of treatment ... Read more

January 18, 2025January 18, 2025

Toward alpha-synuclein seed amplification assay in clinical practice.

Parkinson's Disease Literature

Publication date: Jan 17, 2025 Seed amplification assays (SAAs) demonstrate remarkable diagnostic performance in alpha-synucleinopathies. However, existing protocols lack accessibility in routine laboratories, mainly due to the requirement for in-house ... Read more

January 18, 2025January 18, 2025

Investigating amygdala nuclei volumes in military personnel with post-traumatic stress disorder, major depressive disorder, and adjustment disorder: A retrospective cross-sectional study using clinical routine data.

Major Depressive Disorder Literature

Publication date: Jan 17, 2025 Post-traumatic Stress Disorder (PTSD), Major Depressive Disorder (MDD), and Adjustment Disorder (AdjD) are highly prevalent among military personnel, often presenting diagnostic challenges due to overlapping ... Read more

January 18, 2025January 18, 2025

Ketamine and Esketamine in Clinical Trials: FDA-Approved and Emerging Indications, Trial Trends With Putative Mechanistic Explanations.

Major Depressive Disorder Literature

Publication date: Feb 01, 2025 Ketamine has a long and very eventful pharmacological history. Its enantiomer, esketamine ((S)-ketamine), was approved by the US Food and Drug Administration (FDA) and EMA ... Read more

January 18, 2025January 18, 2025

HIV clinical outcomes among people with HIV and diabetes mellitus in Kampala, Uganda; A matched retrospective cohort study.

Tuberculosis Literature

Publication date: Jan 17, 2025 Suppressive antiretroviral treatment (ART) has resulted into prolonged survival of people with HIV (PWH) in Sub-Saharan Africa (SSA) with resultant increase in the incidence of ... Read more

January 18, 2025January 18, 2025

Antibiotic treatment for drug-resistant tuberculosis found to be safe and effective in clinical trial

Tuberculosis News

Publication date: Jan 18, 2025 The trial findings were combined with a second trial, TB-CHAMP, that took place in South Africa and involved the same treatment in children. Jointly, they ... Read more