Search Results for: Complex

January 18, 2025January 18, 2025

Pigmented Superficial Basal Cell Carcinoma of the Nipple-Areola Complex: A Case Report.

Melanoma Literature

Publication date: Jan 17, 2025 Basal cell carcinoma (BCC) is the most common type of skin malignancy, accounting for approximately 80% of all non-melanoma skin cancers (NMSCs). Ultraviolet (UV) exposure ... Read more

January 17, 2025January 17, 2025

Structural characterization of complex tannins from Euryale ferox fruit peels and their inhibitory mechanisms against tyrosinase activity and melanogenesis.

Melanoma Literature

Publication date: Jan 14, 2025 Tyrosinase is a rate-limiting enzyme for melanogenesis and abnormal melanin production can be controlled by utilizing tyrosinase inhibitory substances. To develop potent and safe inhibitors ... Read more

January 16, 2025January 16, 2025

Complex management of GS (Good’s syndrome) with persistent COVID-19 infection and polymicrobial infections: A case report.

Coronavirus Literature

Publication date: Jan 15, 2025 This case report highlights the diagnostic and therapeutic complexities faced by a 56-year-old female with Good’s syndrome (GS), who presented with persistent Coronavirus Disease 2019 ... Read more

January 16, 2025January 16, 2025

The microcephaly-associated transcriptional regulator AUTS2 cooperates with Polycomb complex PRC2 to produce upper-layer neurons in mice.

Autism Literature

Publication date: Jan 15, 2025 AUTS2 syndrome is characterized by intellectual disability and microcephaly, and is often associated with autism spectrum disorder, but the underlying mechanisms, particularly concerning microcephaly, remain ... Read more

January 14, 2025January 14, 2025

Clinical epidemiology, genetic diversity, and drug susceptibility patterns by whole genome sequencing of Mycobacterium tuberculosis complex isolates in Gabon from 2012 to 2022.

Tuberculosis Literature

Publication date: Mar 01, 2025 This study aimed to investigate genotypic characteristics and drug resistance profiles of Mycobacterium tuberculosis complex (Mtbc) strains isolated from patients with suspected tuberculosis (TB) in ... Read more

January 12, 2025January 12, 2025

Identifying Distinct Developmental Patterns of Brain Complexity in Autism: A Cross-Sectional Cohort Analysis Using the Autism Brain Imaging Data Exchange.

Autism Literature

Publication date: Jan 11, 2025 Autistic traits exhibit neurodiversity with varying behaviors across developmental stages. Brain complexity theory, illustrating the dynamics of neural activity, may elucidate the evolution of autistic ... Read more

January 11, 2025January 11, 2025

Ultrasensitive detection of intact SARS-CoV-2 particles in complex biofluids using microfluidic affinity capture.

Coronavirus Literature

Publication date: Jan 10, 2025 Measuring virus in biofluids is complicated by confounding biomolecules coisolated with viral nucleic acids. To address this, we developed an affinity-based microfluidic device for specific ... Read more

January 11, 2025January 11, 2025

Whole-genome phylogenetic analysis of Mycobacterium avium complex from clinical respiratory samples.

Tuberculosis Literature

Publication date: Jan 10, 2025 The Mycobacterium avium complex (MAC) is a common causative agent causing nontuberculous mycobacterial (NTM) pulmonary disease worldwide. Whole-genome sequencing was performed on a total of ... Read more

January 10, 2025January 10, 2025

Artificial intelligence-driven hydrogel microneedle patches integrating 5-fluorouracil inclusion complex-loaded flexible pegylated liposomes for enhanced non-melanoma skin cancer treatment.

Melanoma Literature

Publication date: Jan 25, 2025 The current study focused on the development of crosslinked hydrogel microneedle patches (cHMNs) incorporating 5-FU-hydroxypropyl beta-cyclodextrin inclusion complex-loaded flexible PEGylated liposomes (5-FU-HPβCD-loaded FP-LPs) to enhance ... Read more

January 10, 2025January 10, 2025

Affinity Tag-Free Purification of SARS-CoV-2 N Protein and Its Crystal Structure in Complex with ssDNA.

Coronavirus Literature

Publication date: Nov 30, 2024 The nucleocapsid (N) protein is one of the four structural proteins in SARS-CoV-2, playing key roles in viral assembly, immune evasion, and stability. One of ... Read more