Search Results for: Concept

January 16, 2025January 16, 2025

Large Language Models Struggle to Encode Medical Concepts – A Multilingual Benchmarking and Comparative Analysis

Dr. Richard A. Blevins News, Informatics News

Publication date: Jan 14, 2025 Interoperability in health information systems is crucial for accurate data exchange across environments such as electronic health records, clinical notes, and medical research. The main ... Read more

January 10, 2025January 10, 2025

Phase II Proof-of-concept, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Plitidepsin in Adults with Post-COVID-19 Condition (PCC)

Coronavirus News

Publication date: Jan 08, 2025 The study aims to prove that plitidepsin could be an efficacious, safe, and well-tolerated therapy for PCC. To this end, we will perform a randomized, ... Read more

January 10, 2025January 10, 2025

Biomedical Relation Extraction via Adaptive Document-Relation Cross-Mapping and Concept Unique Identifier

Dr. Richard A. Blevins News, Informatics News

Publication date: Jan 09, 2025 Document-Level Biomedical Relation Extraction (Bio-RE) aims to identify relations between biomedical entities within extensive texts, serving as a crucial subfield of biomedical text mining. Existing ... Read more

January 7, 2025January 7, 2025

mRNA vaccines in the context of cancer treatment: from concept to application.

Coronavirus Literature

Publication date: Jan 06, 2025 Immuno-oncology has witnessed remarkable advancements in the past decade, revolutionizing the landscape of cancer therapeutics in an encouraging manner. Among the diverse immunotherapy strategies, mRNA ... Read more

January 4, 2025January 4, 2025

Pregnancy outcomes after all mode of conception in patients with genital tuberculosis: a systematic review and meta-analysis.

Tuberculosis Literature

Publication date: Jan 03, 2025 This systematic review and meta-analysis aimed to summarize the pregnancy outcomes of women di-agnosed with genital tuberculosis (GTB) who spontaneously conceived or underwent intrauterine in-semination ... Read more

December 28, 2024December 28, 2024

A stratified treatment algorithm in psychiatry: a program on stratified pharmacogenomics in severe mental illness (Psych-STRATA): concept, objectives and methodologies of a multidisciplinary project funded by Horizon Europe.

Major Depressive Disorder Literature

Publication date: Dec 27, 2024 Schizophrenia (SCZ), bipolar (BD) and major depression disorder (MDD) are severe psychiatric disorders that are challenging to treat, often leading to treatment resistance (TR). It ... Read more

December 27, 2024December 27, 2024

Long-COVID – pathophysiology, current concepts and future directions.

Coronavirus Literature

Publication date: Dec 24, 2024 Long-COVID, an umbrella term referring to a variety of symptoms and clinical presentations, which emerge in a subset of patients after SARS-CoV-2 infection, has a ... Read more

December 18, 2024December 18, 2024

Preclinical Proof of Concept for SNAPTM-TIL: a personalized, next-generation tumor-infiltrating lymphocyte therapy platform

Melanoma News

Publication date: Dec 16, 2024 Tumor-infiltrating lymphocyte (TIL) therapy, which involves extracting, expanding, and reinfusing immune cells to target cancer cells, has shown promise in melanoma treatment, but requires optimization ... Read more

December 17, 2024December 17, 2024

Navigating triplet repeats sequencing: concepts, methodological challenges and perspective for Huntington’s disease.

Huntington's Disease Literature

Publication date: Dec 16, 2024 The accurate characterization of triplet repeats, especially the overrepresented CAG repeats, is increasingly relevant for several reasons. First, germline expansion of CAG repeats above a ... Read more

December 17, 2024December 17, 2024

Preconception and gestational versus postnatal exposure to air pollutants and risk of autism spectrum disorder: a systematic review and meta-analysis.

Autism Literature

Publication date: Dec 15, 2024 The rising prevalence of ASD has prompted extensive research into potential environmental risk factors, with air pollution particularly emerging as a major concern. A systematic ... Read more