Publication date: Jan 01, 2025 Coronaviruses replicate by using the 3C-like protease (3CL) to cleave polyprotein precursors and host proteins. However, current tools for identifying 3CL cleavage sites are limited, ... Read more

Publication date: Feb 01, 2025 Limited genomic surveillance data is available for SARS-CoV-2 in Thailand during the second and third wave outbreaks, including both patient and environmental samples. This study ... Read more

Publication date: Dec 06, 2024 Middle East respiratory syndrome coronavirus (MERS-CoV) circulates in dromedary camels in the Arabian Peninsula and occasionally causes spillover infections in humans. MERS-CoV diversity is poorly ... Read more

Publication date: Dec 06, 2024 Swine enteric coronaviruses pose a significant challenge to the global pig industry, inflicting severe diarrhea and high mortality rates among piglets, and resulting in substantial ... Read more

Publication date: Dec 03, 2024 Equine Coronavirus (ECoV) can cause gastrointestinal disease and was first described in 2000 in the USA followed by several international outbreak case reports. Disease manifestation ... Read more

Publication date: Dec 01, 2024 Illuminated by insights into the hijacking of host cellular metabolism by coronaviruses, we identified an initial hit compound 7030B-C5, characterized by a xanthine scaffold, via ... Read more

Publication date: Dec 03, 2024 Bariatric/metabolic surgery has been reported to reduce the incidence of severe coronavirus disease 2019 (COVID-19); however, its ability to reduce risk is controversial. Therefore, this ... Read more

Publication date: Dec 01, 2024 Porcine deltacoronavirus (PDCoV) is a coronavirus that causes diarrhea in suckling piglets and has the potential for cross-species transmission. Monitoring PDCoV evolution and identifying potential ... Read more

Publication date: Dec 01, 2024 The development of acute humoral rejection (AMR) in transplanted organs remains a highly relevant and unresolved issue. This study presents a clinical case of heart ... Read more

Publication date: Nov 30, 2024 Human coronaviruses exhibit a spectrum of symptoms, ranging from mild seasonal colds to severe respiratory manifestations. Despite progress in understanding the host’s innate defense mechanisms ... Read more