Search Results for: Cox
Persistent COX-2 upregulation in L-DOPA-induced dyskinesia is unaffected by inhibition with celecoxib.
Parkinson's Disease Literature
Publication date: Jun 15, 2025 Neuroinflammation is a major contributor to L-DOPA-induced dyskinesia (LID), a common complication in Parkinson’s disease (PD) therapy. Cyclooxygenase-2 (COX-2), a key proinflammatory enzyme, is elevated ... Read more
Pelvic support osteotomy with subsequent femoral lengthening: a reliable treatment for late tuberculous coxitis in skeletally immature patients.
Tuberculosis Literature
Publication date: Jun 14, 2025 Tuberculous (TB) coxitis, constituting 15-20% of musculoskeletal tuberculosis cases, often leads to late-stage complications. Joint replacement yields unsatisfactory results. This study aims to know about ... Read more
Association Between Ovarian Sex Cord-Stromal Tumors and Non-Hormone-Sensitive Cancers: A Nationwide Nested Cohort Study.
Melanoma Literature
Publication date: Jul 15, 2025 Ovarian sex cord-stromal cell tumors (SCSTs) are a rare group of ovarian neoplasms that include both benign and malignant diseases. Previous studies found an increased ... Read more
[Overexpression of multimerin-2 promotes cutaneous melanoma cell invasion and migration and is associated with poor prognosis].
Melanoma Literature
Publication date: Jul 20, 2025 To investigate the inhibitory effect of multimerin-2 (MMRN2) overexpression on growth and metastasis of cutaneous melanoma cells. Clinical data of patients with cutaneous melanoma were ... Read more
Association of ultra-processed food consumption with prodromal, incident Parkinson’s disease and mortality.
Parkinson's Disease Literature
Publication date: Jul 17, 2025 Ultra-processed foods (UPFs), widely consumed globally, are increasingly recognised as a key factor in poor dietary quality and diet-related health risks. However, little is known ... Read more
SGLT2 inhibitors vs. metformin for Parkinson’s disease risk reduction in type 2 diabetes.
Parkinson's Disease Literature
Publication date: Jul 17, 2025 SummaryThis study is the first large-scale, head-to-head comparison suggesting that sodium-glucose cotransporter-2 inhibitors (SGLT2is) may offer greater neuroprotection against Parkinson’s disease (PD) compared to metformin ... Read more
Explainable machine learning-driven models for predicting Parkinson’s disease and its prognosis: obesity patterns associations and models development using NHANES 1999-2018 data.
Parkinson's Disease Literature
Publication date: Jul 17, 2025 Parkinson’s disease (PD) is a prevalent neurodegenerative condition, the effect of obesity on PD remains controversial. We aimed to investigate the associations of obesity patterns ... Read more
Association of Nirmatrelvir/Ritonavir and the Risk of Long COVID Among US Adults: A Multicenter Retrospective Cohort Study.
Coronavirus Literature
Publication date: Jul 01, 2025 Nirmatrelvir/ritonavir (NMV-r) is an oral antiviral agent authorized for treating acute COVID-19, but its effectiveness in reducing long COVID risk remains uncertain. This multicenter retrospective ... Read more
Socio-economic inequalities in all-cause mortality during the COVID-19 period in north-western Tanzania, 2018-2021.
Coronavirus Literature
Publication date: Jul 14, 2025 Evidence suggests that the COVID-19 pandemic has exacerbated social and demographic inequalities in the communities through pathways of unequal exposure, vulnerability, and susceptibility. In Tanzania, ... Read more