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Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have potential to transform health outcomes for persons with bipolar disorder, schizophrenia, Major depressive disorder and other serious mental illnesses by lengthening healthspan and reducing excess and premature mortality.

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have potential to transform health outcomes for persons with bipolar disorder, schizophrenia, Major depressive disorder and other serious mental illnesses by lengthening healthspan and reducing excess and premature mortality.

Major Depressive Disorder Literature
Publication date: Jan 21, 2026 Open Access PDF Concepts Keywords Genes bipolar disorder Healthspan cardiovascular Lengthening GLP-1 Pharmacother glucagon Schizophrenia major depressive disorder metabolism mortality schizophrenia semaglutide type 2 diabetes ... Read more