Search Results for: Diethylstilbestrol

January 21, 2025January 21, 2025

Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications.

Publication date: Jan 18, 2025 Chitinase-3-like-1 (CHI3L1) is an evolutionarily conserved protein involved in key biological processes, including tissue remodeling, angiogenesis, and neuroinflammation. It has emerged as a significant player ... Read more

January 21, 2025January 21, 2025

TMS in major depression: A retrospective naturalistic study including two subjective tools.

Major Depressive Disorder Literature

Publication date: Jan 20, 2025 To report the outcomes of transcranial magnetic stimulation (TMS) treatment of patients with acute major depressive disorder (MDD), with particular attention to the performance of ... Read more

January 21, 2025January 21, 2025

A comprehensive graph neural network method for predicting triplet motifs in Disease-Drug-Gene interactions.

Dr. Richard A. Blevins Literature, Informatics Literature

Publication date: Jan 20, 2025 The drug-disease, gene-disease, and drug-gene relationships, as high-frequency edge types, describe complex biological processes within the biomedical knowledge graph. The structural patterns formed by these ... Read more

January 19, 2025January 19, 2025

Are psychological attitudes towards vaccination an expression of personality? A cross-sectional study on COVID-19 vaccination in France.

Coronavirus Literature

Publication date: Jan 17, 2025 The capacity of the 7C model’s psychological antecedents, which include confidence in vaccines, complacency, convenience, calculation, collective responsibility, confidence in the wider system, and social ... Read more

January 19, 2025January 19, 2025

Discordance, accuracy and reproducibility study of pathologists’ diagnosis of melanoma and melanocytic tumors.

Melanoma Literature

Publication date: Jan 17, 2025 Accurate melanoma diagnosis is crucial for patient outcomes and reliability of AI diagnostic tools. We assess interrater variability among eight expert pathologists reviewing histopathological images ... Read more

January 19, 2025January 19, 2025

Exploring the anticancer activities of Sulfur and magnesium oxide through integration of deep learning and fuzzy rough set analyses based on the features of Vidarabine alkaloid.

Melanoma Literature

Publication date: Jan 17, 2025 Drug discovery and development is a challenging and time-consuming process. Laboratory experiments conducted on Vidarabine showed IC 6. 97 ug∕mL, 25. 78 ug∕mL, and ˃ ... Read more

January 19, 2025January 19, 2025

Changes in sensor recorded activity patterns and neuropsychiatric symptoms after deep brain stimulation for Parkinson’s disease: 5 case reports.

Parkinson's Disease Literature

Publication date: Jan 17, 2025 Effects of subthalamic nucleus deep brain stimulation (STN-DBS) on neuropsychiatric symptoms of Parkinson’s disease (PD) remain debated. Sensor technology might help to objectively assess behavioural ... Read more

January 19, 2025January 19, 2025

Factors of progression to severity and death in COVID-19 patients at two health care sites in Bamako, Mali.

Coronavirus Literature

Publication date: Jan 17, 2025 To analyze the clinical and biological characteristics and to evaluate the risk factors associated with the mortality of patients with COVID-19 in Commune IV of ... Read more

January 18, 2025January 18, 2025

In-silico screening and analysis of missense SNPs in human CYP3A4/5 affecting drug-enzyme interactions of FDA-approved COVID-19 antiviral drugs.

Coronavirus Literature

Publication date: Jan 16, 2025 Single nucleotide polymorphisms (SNPs) represent the prevailing form of genetic variations observed in the human population. Such variations could alter the encoded enzymes’ activities. CYP3A4/5 ... Read more

January 18, 2025January 18, 2025

Evaluating the impact of COVID-19 protection measures and staff absence on radiotherapy practice: A simulation study.

Coronavirus Literature

Publication date: Jan 17, 2025 Radiotherapy practice for cancer treatment is resource-intensive and demands optimised processes for patient throughput while guaranteeing the quality and safety of the therapy. With the ... Read more