Search Results for: Diverse

January 16, 2025January 16, 2025

Genome-wide study of major depression in 685,808 diverse individuals identifies 697 independent associations, infers causal neuronal subtypes and biological targets for novel pharmacotherapies.

Publication date: Jan 14, 2025 In a genome-wide association study (GWAS) meta-analysis of 685,808 individuals with major depression (MD) and 4,364,225 controls from 29 countries and across diverse and admixed ... Read more

January 14, 2025January 14, 2025

Diverse strategies utilized by coronaviruses to evade antiviral responses and suppress pyroptosis.

Coronavirus Literature

Publication date: Jan 09, 2025 Viral infections trigger inflammasome-mediated caspase-1 activation. Nevertheless, limited understanding exists regarding how viruses use the active caspase-1 to evade host immune response. Here, we use ... Read more

January 14, 2025January 14, 2025

The birth of the virtual clinic: welcome to the Mediverse.

Coronavirus Literature

Publication date: Jan 13, 2025 The COVID-19 pandemic triggered a global pivot to virtual care (VC) technologies. While there has been considerable academic work exploring the “how” of VC, few ... Read more

January 14, 2025January 14, 2025

Drug carrier-assisted combined chemo- and radionuclide therapy for tumors of diverse origins: effects of therapeutic schemes on tumor responses.

Melanoma Literature

Publication date: Jan 13, 2025 Despite the promising results in cancer treatment, standard monotherapy remains insufficient for a wide range of oncological diseases. Combined therapy can significantly improve therapeutic outcomes ... Read more

January 10, 2025January 10, 2025

Cancer-related health behaviors during the COVID 19 pandemic in geographically diverse samples across the US.

Coronavirus Literature

Publication date: Jan 09, 2025 The COVID-19 pandemic involved business closures (e. g., gyms), social distancing policies, and prolonged stressful situations that may have impacted engagement in health behaviors. Our ... Read more

January 10, 2025January 10, 2025

Antimelanoma differentiation-associated gene 5 (anti-MDA5) antibody-positive dermatomyositis: clinical features and outcomes in a racially diverse patient cohort.

Melanoma Literature

Publication date: Jan 09, 2025 The anti-melanoma differentiation-associated gene 5 (anti-MDA5) antibody-positive dermatomyositis is known for its association with rapidly progressive interstitial lung disease (RP-ILD) and ulcerative skin lesions, often ... Read more

January 7, 2025January 7, 2025

Prevalence of and factors associated with long COVID among diverse healthcare workers in the UK: a cross-sectional analysis of a nationwide study (UK-REACH).

Coronavirus Literature

Publication date: Jan 06, 2025 To assess the prevalence of UK healthcare workers (HCWs) who reported symptoms of COVID-19 lasting for longer than 5 weeks and examine associated factors with experiencing ... Read more

January 1, 2025January 1, 2025

Cytokine-armed pyroptosis induces antitumor immunity against diverse types of tumors.

Melanoma Literature

Publication date: Dec 30, 2024 Inflammasomes are defense complexes that utilize cytokines and immunogenic cell death (ICD) to stimulate the immune system against pathogens. Inspired by their dual action, we ... Read more

January 1, 2025January 1, 2025

Sociodemographic characteristics of SARS-CoV-2 serosurveillance studies with diverse recruitment strategies, Canada, 2020 to 2023

Coronavirus News

Publication date: Dec 30, 2024 Background. Serological testing was a key component of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) surveillance. Social distancing interventions, resource limitations, and the need for timely ... Read more

December 27, 2024December 27, 2024

N-terminus α-synuclein detection reveals new and more diverse aggregate morphologies in multiple system atrophy and Parkinson’s disease.

Parkinson's Disease Literature

Publication date: Dec 27, 2024 Parkinson’s disease (PD) and multiple system atrophy (MSA) are classified as α-synucleinopathies and are primarily differentiated by their clinical phenotypes. Delineating these diseases based on ... Read more