Search Results for: Dopamine

March 25, 2020March 25, 2020

Intraventricular dopamine infusion alleviates motor symptoms in a primate model of Parkinson’s disease.

Publication date: Mar 20, 2020 Continuous compensation of dopamine represents an ideal symptomatic treatment for Parkinson’s disease (PD). The feasibility in intracerebroventricular administration (i.c.v.) of dopamine previously failed because of ... Read more

March 25, 2020

[F]-DPA-714 PET as a specific in vivo marker of early microglial activation in a rat model of progressive dopaminergic degeneration.

Parkinson's Disease Literature

Publication date: Mar 23, 2020 To study the feasibility of the in vivo -DPA-714 TSPO positron emission tomography (PET) to detect glial activation in a rat model of progressive parkinsonism ... Read more

March 24, 2020

Separating dopamine D and D receptor sources of [C]-(+)-PHNO binding potential: Independent component analysis of competitive binding.

Parkinson's Disease Literature

Publication date: Mar 19, 2020 Development of medications selective for dopamine D or D receptors is an active area of research in numerous neuropsychiatric disorders including addiction and Parkinson’s disease. ... Read more

March 24, 2020March 24, 2020

Dopaminergic medication improves cognitive control under low cognitive demand in Parkinson’s disease.

Parkinson's Disease Literature

Publication date: Mar 23, 2020 Dopamine agonists are the main pharmacological intervention for the motor symptoms of Parkinson’s disease (PD). However, dopaminergic medication has been associated with disinhibitory psychopathology in ... Read more

March 23, 2020March 23, 2020

Physical exercise protects against mitochondria alterations in the 6-hidroxydopamine rat model of Parkinson’s disease.

Parkinson's Disease Literature

Publication date: Mar 18, 2020 Parkinson’s disease (PD) is typicaly caractherized by loss of dopaminergic neurons, as well as the presence of mitochondrial impairments. Although physical exercise is known to ... Read more

March 20, 2020March 20, 2020

Striatal Dopamine Denervation Impairs Gait Automaticity in Drug-Naïve Parkinson’s Disease Patients.

Parkinson's Disease Literature

Publication date: Mar 12, 2020 Gait automaticity, which is impaired in patients with Parkinson’s disease (PD), can be quantified by gait variability analysis. Among the 3 regions of the striatum ... Read more

March 20, 2020March 20, 2020

Dopamine-Evoked Synaptic Regulation in the Nucleus Accumbens Requires Astrocyte Activity.

Parkinson's Disease Literature

Publication date: Mar 18, 2020 Dopamine is involved in physiological processes like learning and memory, motor control and reward, and pathological conditions such as Parkinson’s disease and addiction. In contrast ... Read more

March 19, 2020

miR-7 Controls the Dopaminergic/Oligodendroglial Fate through Wnt/β-catenin Signaling Regulation.

Parkinson's Disease Literature

Publication date: Mar 13, 2020 During the development of the central nervous system, the proliferation of neural progenitors and differentiation of neurons and glia are tightly regulated by different transcription ... Read more

February 7, 2020February 7, 2020

Overeating and food addiction in Major Depressive Disorder: Links to peripheral dopamine.

Major Depressive Disorder Literature

Publication date: Jan 09, 2020 The concept of food addiction refers to addiction-like behaviours that develop in association with the intake of highly palatable foods. Previous research indicates that a ... Read more

January 31, 2020January 31, 2020

Sex-dependent association of urate on the patterns of striatal dopamine depletion in Parkinson’s disease.

Parkinson's Disease News

Publication date: Jan 31, 2020 The ISR was negatively correlated with the serum UA levels in all patients with PD (r = -0. 156, p = 0. 045), and this ... Read more