Search Results for: Gene

December 8, 2019December 8, 2019

Blue light-triggered optogenetic system for treating uveal melanoma.

Melanoma Literature

Publication date: Dec 06, 2019 Uveal melanoma is the most common intraocular primary malignancy in adults and has been considered a fatal disease for decades. Optogenetics is an emerging technique ... Read more

December 8, 2019December 8, 2019

Polydeoxyribonucleotide Activates Mitochondrial Biogenesis but Reduces MMP-1 Activity and Melanin Biosynthesis in Cultured Skin Cells.

Melanoma Literature

Publication date: Dec 07, 2019 The regulation of mitochondrial biogenesis, melanogenesis, and connective tissue proteins is critical for homeostasis and aging skin cells. We examined the biological effects of polydeoxyribonucleotide ... Read more

December 8, 2019

In Vitro Conversion Assays Diagnostic for Neurodegenerative Proteinopathies.

Parkinson's Disease Literature

Publication date: Dec 06, 2019 In vitro conversion assays, including real-time quaking-induced conversion (RT-QuIC) and protein misfolding cyclic amplification (PMCA) techniques, were first developed to study the conversion process of ... Read more

December 7, 2019December 7, 2019

Healthcare utilisation in general practice and hospitals in the year preceding a diagnosis of cancer recurrence or second primary cancer: a population-based register study.

Melanoma Literature

Publication date: Dec 05, 2019 The organisation of cancer follow-up is under scrutiny in many countries, and general practice is suggested to become more involved. A central focus is timely ... Read more

December 7, 2019December 7, 2019

WEBINAR “Genetics in Parkinson’s Disease – Lessons from a Global Cohort”

Parkinson's Disease Media

Publication date: Dec 06, 2019 Watch Dr. Peter Bauer, MD, Chief Scientific Officer at CENTOGENE, as he introduces Parkinson?s Disease (PD) and outlines genetic screening options for PD. You will ... Read more

December 7, 2019December 7, 2019

The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration.

Parkinson's Disease Literature

Publication date: Dec 05, 2019 Metabolic dysfunction and neuroinflammation are increasingly implicated in Parkinson’s disease (PD). The pentose phosphate pathway (PPP, a metabolic pathway parallel to glycolysis) converts glucose-6-phosphate into ... Read more

December 6, 2019December 6, 2019

The interplay of sun-damage and genetic risk in Australian multiple and single primary melanoma cases and controls.

Melanoma Literature

Publication date: Dec 03, 2019 Skin phenotype, host genotype and UV damage play a role in development of melanoma. To ascertain whether the level of UV damage at the site ... Read more

December 6, 2019December 6, 2019

Next Generation Sequencing (NGS): A Revolutionary Technology in Pharmacogenomics and Personalized Medicine in Cancer.

Precision Medicine Literature

Publication date: Nov 13, 2019 Following the completion of the Human Genome Project in 2003, research in oncology has progressively focused on the sequencing of cancer genomes, with the aim ... Read more

December 6, 2019December 6, 2019

Two precision medicine predictive tools for six malignant solid tumors: from gene-based research to clinical application.

Precision Medicine Literature

Publication date: Dec 03, 2019 The current study aimed to construct competing endogenous RNA (ceRNA) regulation network and develop two precision medicine predictive tools for colorectal cancer (CRC). Differentially expressed ... Read more

December 6, 2019December 6, 2019

Cutting neurodegeneration associated with dementia, in animal models

Parkinson's Disease News

Publication date: Nov 26, 2019 The Korea Brain Research Institute (KBRI, President Pann Ghill Suh) announced on November 12 that korean research team made up of Dr. Hyung-Jun Kim and ... Read more