Search Results for: Glucocorticoids

December 2, 2024December 2, 2024

Latent Class Analysis Reveals, in patient profiles, COVID-19-related better prognosis by calcifediol treatment than glucocorticoids.

Publication date: Jan 01, 2025 Calcifediol and glucocorticoids have been repositioned for the treatment of COVID-19 and may reduce severity, the need for intensive care unit admission and death. to ... Read more

October 28, 2024October 28, 2024

Glucocorticoids induce HMGB1 release in primary cultured rat cortical microglia.

Major Depressive Disorder Literature

Publication date: Nov 12, 2024 Stress, a risk factor for major depressive disorder and Alzheimer disease, leads to the release of high-mobility group box-1 (HMGB1) protein, which in turn causes ... Read more

January 10, 2025January 10, 2025

Characteristics, risk factors and a risk prediction model of tocilizumab-induced hypofibrinogenemia: a retrospective real-world study of inpatients.

Coronavirus Literature

Publication date: Jan 09, 2025 The occurrence of hypofibrinogenemia after tocilizumab treatment has attracted increasing attention, which may cause bleeding and even life-threatening. This study aims to explore the risk ... Read more

January 9, 2025January 9, 2025

Targeting the NLRP3 inflammasome abrogates cardiotoxicity of immune checkpoint blockers.

Melanoma Literature

Publication date: Jan 07, 2025 Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of many malignant tumors. However, ICI-induced hyper-immune activation causes cardiotoxicity. Traditional treatments such as glucocorticoids and immunosuppressants ... Read more

January 7, 2025January 7, 2025

[Chinese expert consensus on the diagnosis and treatment of pneumonia in the elderly (2024 Edition)].

Coronavirus Literature

Publication date: Jan 12, 2025 China is experiencing a demographic shift as its population ages. The elderly population becomes increasingly susceptible to pneumonia. Pneumonia in the elderly is characterized by ... Read more

January 7, 2025January 7, 2025

[Septic musculoskeletal complications under immunomodulating treatment].

Tuberculosis Literature

Publication date: Jan 06, 2025 Infections are an important cause of morbidity and mortality in patients with inflammatory rheumatic diseases. Among these, musculoskeletal infections represent a relevant proportion as patients ... Read more

January 6, 2025January 6, 2025

Common drugs given to millions of pregnant women at risk of preterm births linked to autism in children

Autism News

Publication date: Jan 06, 2025 The study included two main groups of mothers: those given steroids to prevent premature birth, and a larger group who received the drugs to treat ... Read more

December 20, 2024December 20, 2024

Early Antiviral Use and Supplemental Oxygen Decrease the Risk of Secondary Bacterial Infections: A Multicentre Nested Case-Control Study.

Coronavirus Literature

Publication date: Dec 17, 2024 To evaluate the treatment strategies that dictate the host susceptibility to secondary bacterial infections during coronavirus disease 2019 (COVID-19). Setting and Participants: This nested case-control ... Read more

December 19, 2024December 19, 2024

[COVID-19 vaccines efficacy and infection features in patients with systemic sclerosis: A single-center cohort study].

Coronavirus Literature

Publication date: Dec 18, 2024 To comprehensively understand the COVID-19 vaccination and infection status among patients with systemic sclerosis (SSc). We conducted a retrospective analysis of patients diagnosed with SSc ... Read more

December 14, 2024December 14, 2024

Neuroprotective Effects of Dexamethasone in a Neuromelanin-Driven Parkinson’s Disease Model.

Parkinson's Disease Literature

Publication date: Dec 14, 2024 Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra that primarily affects movement control. Neuroinflammation plays a pivotal ... Read more