Search Results for: Hepatitis

August 13, 2022August 13, 2022

PD-1 Inhibitors With or Without Radiation in Advanced Melanoma

Melanoma News

Publication date: Aug 12, 2022 This trial was a single-center, prospective, randomized controlled phase II trial. The objective was to evaluate the efficacy and safety of PD-1 inhibitors with or ... Read more

August 13, 2022August 13, 2022

Study of CBL0137 in Combination With Ipilimumab and Nivolumab Therapy in Melanoma

Melanoma News

Publication date: Aug 12, 2022 Phase I, open label, dose-escalation, and safety study designed to assess the safety and biologic activity of the investigational agent CBL0137 in combination with standard ... Read more

August 12, 2022August 12, 2022

Targeted Alpha Particle Radiotherapy for Metastatic Uveal Melanoma

Melanoma News

Publication date: Aug 11, 2022 The primary aim of the study is to establish the maximum-tolerated dose (MTD) of 225Ac-MTI-201 in participants with metastatic uveal melanoma. The secondary aims are ... Read more

August 9, 2022August 9, 2022

START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer

Melanoma News

Publication date: Aug 08, 2022 This study is being conducted to explore the immunological mechanism of action of Peptide-coated Conditionally Replicating Adenovirus-1 (PeptiCRAd-1) plus Checkpoint inhibitor (CPI) therapy in multiple ... Read more

August 7, 2022August 7, 2022

Neoadjuvant nivolumab + T-VEC combination therapy for resectable early stage or metastatic (IIIB-IVM1a) melanoma with injectable disease: study protocol of the NIVEC trial.

Melanoma Literature

Publication date: Aug 04, 2022 Trials investigating neoadjuvant treatment with immune checkpoint inhibitors (ICI) in patients with melanoma have shown high clinical and pathologic response rates. Treatment with talimogene laherparepvec ... Read more

August 5, 2022August 5, 2022

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Melanoma News

Publication date: Aug 04, 2022 The purpose of this study is to evaluate the safety, pharmacokinetics (PK), and activity of GDC-1971 when administered in combination with atezolizumab in participants with ... Read more

August 3, 2022August 3, 2022

Open Label Phase 2 Basket Trial With Atezolizumab and Tiragolumab in Solid Tumors

Melanoma News

Publication date: Aug 02, 2022 In this open label phase II trial combination therapy with the anti-PD-L1 antibody atezolizumab and the anti-TIGIT antibody tiragolumab will be investigated in patients with ... Read more

August 2, 2022August 2, 2022

Olaparib in Unresectable/Metastatic Melanoma With BRCA1/2

Melanoma News

Publication date: Aug 01, 2022 The purpose of this study is to evaluate how effective Olaparib is when given as a treatment for primary or recurrent, unresectable or metastatic melanoma. ... Read more

July 30, 2022July 30, 2022

Dose Escalation Study of WTX-124 as Monotherapy and in Combination With Pembrolizumab (Pembro) in Patients With Selected Advanced or Metastatic Solid Tumors

Melanoma News

Publication date: Jul 29, 2022 A first-in-human, Phase I, open-label, multicenter study of WTX-124 administered as monotherapy and in combination with pembrolizumab to patients with advanced solid tumors. Concepts Keywords ... Read more

July 21, 2022July 21, 2022

PD-1 Antibody Tislelizumab Combined With Dacarbazine in the Treatment of Advanced Melanoma

Melanoma News

Publication date: Jul 20, 2022 A total of 40 subjects who had not received systemic treatment or chemotherapy in the past and were allowed to receive adjuvant or neoadjuvant treatment ... Read more