Search Results for: Homeostasis

January 10, 2025January 10, 2025

Physiological and molecular impairment of PV circuit homeostasis in mouse models of autism

Autism News

Publication date: Jan 08, 2025 Circuit dysfunction in autism may involve a failure of homeostatic plasticity. To test this, we studied parvalbumin (PV) interneurons which exhibit rapid homeostatic plasticity of ... Read more

December 31, 2024December 31, 2024

CLEC12B regulates melanocyte immunity and homeostasis in the skin through the STAT1/IRF1 axis.

Melanoma Literature

Publication date: Dec 28, 2024 CLEC12B is a C-type lectin receptor involved in the inhibition of natural killers-mediated cytotoxicity. We have previously shown that CLEC12B is predominantly expressed on melanocytes, ... Read more

December 24, 2024December 24, 2024

Copper homeostasis and neurodegenerative diseases.

Huntington's Disease Literature

Publication date: Nov 01, 2025 Copper, one of the most prolific transition metals in the body, is required for normal brain physiological activity and allows various functions to work normally ... Read more

December 4, 2024December 4, 2024

Environmental fungi target thiol homeostasis to compete with Mycobacterium tuberculosis.

Tuberculosis Literature

Publication date: Dec 01, 2024 Mycobacterial species in nature are found in abundance in sphagnum peat bogs where they compete for nutrients with a variety of microorganisms including fungi. We ... Read more

December 3, 2024December 3, 2024

Iron homeostasis and neurodegeneration in the ageing brain: Insight into ferroptosis pathways.

Huntington's Disease Literature

Publication date: Dec 01, 2024 Ageing is a major risk factor for various chronic diseases and offers a potential target for developing novel and broadly effective preventatives or therapeutics for ... Read more

November 23, 2024November 23, 2024

Dynamic Thiol-Disulfide Homeostasis Post-COVID-19 Depends on Age, Gender, and Symptom Severity.

Coronavirus Literature

Publication date: Oct 01, 2024 It has been indicated that the thiol-disulfide homeostasis plays a role in the pathogenesis of COVID-19 infection. We assessed the impact on the thiol-disulfide homeostasis ... Read more

November 21, 2024November 21, 2024

Copper homeostasis and cuproptosis in central nervous system diseases.

Huntington's Disease Literature

Publication date: Nov 21, 2024 Copper (Cu), an indispensable micronutrient for the sustenance of living organisms, contributes significantly to a vast array of fundamental metabolic processes. The human body maintains ... Read more

November 16, 2024November 16, 2024

Targeting protein homeostasis with small molecules as a strategy for the development of pan-coronavirus antiviral therapies.

Coronavirus Literature

Publication date: Nov 07, 2024 The COVID-19 pandemic has created a global health crisis, with challenges arising from the ongoing evolution of the SARS-CoV-2 virus, the emergence of new strains, ... Read more

November 16, 2024November 16, 2024

Targeting protein homeostasis with small molecules as a strategy for the development of pan-coronavirus antiviral therapies.

Coronavirus Literature

November 16, 2024November 16, 2024

Targeting protein homeostasis with small molecules as a strategy for the development of pan-coronavirus antiviral therapies.

Coronavirus Literature