Search Results for: Hyaluronic acid

February 20, 2019February 20, 2019

The effects of therapeutic concentrations of gentamicin, amikacin and hyaluronic acid on cultured bone marrow-derived equine mesenchymal stem cells.

Publication date: Nov 01, 2013 Joint inflammation and septic arthritis are both potential complications of intra-articular injections of bone marrow-derived mesenchymal stem cells (BM-MSCs). Clinicians may prophylactically co-inject BM-MSCs admixed ... Read more

October 10, 2018October 10, 2018

Hyaluronic acid-CD44 interactions promote BMP4/7-dependent Id1/3 expression in melanoma cells.

Melanoma Literature

Publication date: Oct 08, 2018 BMP4/7-dependent expression of inhibitor of differentiation/DNA binding (Id) proteins 1 and 3 has been implicated in tumor progression and poor prognosis of malignant melanoma patients. ... Read more

January 12, 2018January 12, 2018

Redox-responsive micelles from disulfide bond-bridged hyaluronic acid-tocopherol succinate for the treatment of melanoma.

Melanoma Literature

Publication date: Jan 06, 2018 Nanotechnology-based chemotherapy is efficient in cancer treatment due to the targeted delivery of small molecules via nano-carriers, which are usually regarded as “inert”. However, nano-materials ... Read more

February 9, 2020February 9, 2020

Transcriptomics of Gabra4 knockout mice reveals common NMDAR pathways underlying autism, memory, and epilepsy.

Autism Literature

Publication date: Feb 07, 2020 Autism spectrum disorder (ASD) is a neuronal developmental disorder with impaired social interaction and communication, often with abnormal intelligence and comorbidity with epilepsy. Disturbances in ... Read more

February 8, 2020

Study of pharmacogenomic information in FDA-approved drug labeling to facilitate application of precision medicine.

Precision Medicine Literature

Publication date: Feb 04, 2020 Pharmacogenomics (PGx), studying the relationship between drug response and genetic makeup of an individual, is accelerating advances in precision medicine. The FDA includes PGx information ... Read more

February 7, 2020

RefDNN: a reference drug based neural network for more accurate prediction of anticancer drug resistance.

Precision Medicine Literature

Publication date: Feb 05, 2020 Cancer is one of the most difficult diseases to treat owing to the drug resistance of tumour cells. Recent studies have revealed that drug responses ... Read more

January 28, 2020

Incremental data integration for tracking genotype-disease associations.

Precision Medicine Literature

Publication date: Jan 27, 2020 Functional annotation of genes remains a challenge in fundamental biology and is a limiting factor for translational medicine. Computational approaches have been developed to process ... Read more

January 22, 2020January 22, 2020

The Adaptive and Innate Immune Cell Landscape of Uterine Leiomyosarcomas.

Melanoma Literature

Publication date: Jan 20, 2020 Reactivation of the anti-tumor response has shown substantial progress in aggressive tumors such as melanoma and lung cancer. Data on less common histotypes are scanty. ... Read more

January 17, 2020

Biomimetic tissue models reveal the role of hyaluronan in melanoma proliferation and invasion.

Melanoma Literature

Publication date: Jan 15, 2020 Interactions of hyaluronan (HA) and tumor and stromal cells are highly discussed as one of the major contributors in tumor progression and metastasis. The balance ... Read more

January 17, 2020

D-tyrosine adds an anti-melanogenic effect to cosmetic peptides.

Melanoma Literature

Publication date: Jan 14, 2020 D-tyrosine is known to negatively regulate melanin synthesis by inhibiting tyrosinase activity. Here, we further reveal that peptides containing terminal D-tyrosine can reduce the melanin ... Read more