Search Results for: Hyaluronic acid

February 20, 2019February 20, 2019

The effects of therapeutic concentrations of gentamicin, amikacin and hyaluronic acid on cultured bone marrow-derived equine mesenchymal stem cells.

Publication date: Nov 01, 2013 Joint inflammation and septic arthritis are both potential complications of intra-articular injections of bone marrow-derived mesenchymal stem cells (BM-MSCs). Clinicians may prophylactically co-inject BM-MSCs admixed ... Read more

October 10, 2018October 10, 2018

Hyaluronic acid-CD44 interactions promote BMP4/7-dependent Id1/3 expression in melanoma cells.

Melanoma Literature

Publication date: Oct 08, 2018 BMP4/7-dependent expression of inhibitor of differentiation/DNA binding (Id) proteins 1 and 3 has been implicated in tumor progression and poor prognosis of malignant melanoma patients. ... Read more

January 12, 2018January 12, 2018

Redox-responsive micelles from disulfide bond-bridged hyaluronic acid-tocopherol succinate for the treatment of melanoma.

Melanoma Literature

Publication date: Jan 06, 2018 Nanotechnology-based chemotherapy is efficient in cancer treatment due to the targeted delivery of small molecules via nano-carriers, which are usually regarded as “inert”. However, nano-materials ... Read more

September 7, 2019September 7, 2019

New compound promotes healing of myelin in nervous system disorders

Multiple Sclerosis News

Publication date: Sep 06, 2019 Credit: Scientists have developed a compound that successfully promotes rebuilding of the protective sheath around nerve cells that is damaged in conditions such as multiple ... Read more

August 29, 2019August 29, 2019

TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling.

Melanoma Literature

Publication date: Aug 27, 2019 We screen ion channels and transporters throughout the genome to identify those required by human melanoma cells but not by normal human melanocytes. We discover ... Read more

August 2, 2019August 2, 2019

Blockade of Lymphangiogenesis Shapes Tumor-Promoting Adipose Tissue Inflammation.

Melanoma Literature

Publication date: Jul 29, 2019 Tumor-associated lymphangiogenesis correlates with lymph node metastasis and poor outcome in several human malignancies. Additionally, the presence of functional lymphatic vessels regulates the formation of ... Read more

July 31, 2019July 31, 2019

The interaction between RE1-silencing transcription factor (REST) and heat shock protein 90 as new therapeutic target against Huntington’s disease.

Huntington's Disease Literature

Publication date: Mar 16, 2019 The wild type huntingtin protein (Htt), supports the production of brain-derived neurotrophic factor (BDNF), a survival factor for striatal neurons, through cytoplasmic sequestering of RE-1silencing ... Read more

July 25, 2019July 25, 2019

CXCL12 loaded-dermal filler captures CXCR4 expressing melanoma circulating tumor cells.

Melanoma Literature

Publication date: Jul 22, 2019 Development of distant metastasis relies on interactions between cancer and stromal cells. CXCL12, also known as stromal-derived factor 1α (SDF-1α), is a major chemokine constitutively ... Read more

July 21, 2019July 21, 2019

Graphing and reporting heterogeneous treatment effects through reference classes

Precision Medicine News

Publication date: Jul 21, 2019 Exploration and modelling of individual treatment effects and treatment heterogeneity is an important aspect of precision medicine in randomized controlled trials (RCTs). The usual approach ... Read more

July 21, 2019July 21, 2019

Graphing and reporting heterogeneous treatment effects through reference classes

Precision Medicine News