Search Results for: L-Valine

June 12, 2025

Enhancing Pulmonary Disease Prediction Using Large Language Models With Feature Summarization and Hybrid Retrieval-Augmented Generation: Multicenter Methodological Study Based on Radiology Report.

Publication date: Jun 11, 2025 The rapid advancements in natural language processing, particularly the development of large language models (LLMs), have opened new avenues for managing complex clinical text data. ... Read more

June 11, 2025

A Critical Reexamination of Recovered SARS-CoV-2 Sequencing Data.

Coronavirus Literature

Publication date: Jun 04, 2025 In 2021, Jesse Bloom published a study addressing why the earliest SARS-CoV-2 sequences in Wuhan from late December 2019 were not those most similar to ... Read more

June 11, 2025

Antimycobacterial Muraymycins Isolated from Streptomyces sp. NRRL 30475 Using OSMAC and Precursor-Feeding Strategies.

Tuberculosis Literature

Publication date: Jun 10, 2025 Three mutant strains of Streptomyces sp. NRRL 30471 were screened with eight different media based on “One Strain Many Compounds” (OSMAC) and precursor-feeding strategies. Five ... Read more

June 10, 2025

Rescue of Epilepsy-Associated Mutations of the Highly Conserved Glycine Residue 443 in the Human GABA Transporter 1.

Autism Literature

Publication date: Jun 15, 2025 The human γ-aminobutyric acid (GABA) transporter 1 (hGAT-1) plays a pivotal role in synaptic neurotransmission by facilitating the clearance of GABA from the synaptic cleft. ... Read more

June 7, 2025

Strategy to overcome a nirmatrelvir resistance mechanism in the SARS-CoV-2 nsp5 protease.

Coronavirus Literature

Publication date: Jun 06, 2025 E166V in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nsp5 protease confers strong resistance to the antiviral component of Paxlovid, nirmatrelvir (NIR), in passaging ... Read more

June 5, 2025

Economic and health consequence frames affect COVID-19 vaccine incentive attitudes in Germany- a survey based framing experiment.

Coronavirus Literature

Publication date: Jun 04, 2025 SARS-CoV-2 vaccines have significantly reduced human and economic losses. Nevertheless, vaccine hesitancy remains a major issue in many countries, including Germany. Recent studies have shown ... Read more

June 4, 2025June 4, 2025

Proinflammatory and GABA eating bacteria in Parkinson’s disease gut microbiome from a meta-analysis prospective.

Parkinson's Disease Literature

Publication date: Jun 03, 2025 Parkinson’s disease (PD) is the second most common neurodegenerative disorder, characterized by motor dysfunction coupled with gastrointestinal disturbances. Recent studies implicate the gut microbiome with ... Read more

June 3, 2025

Structural basis for varying drug resistance of SARS-CoV-2 M E166 variants.

Coronavirus Literature

Publication date: Jun 02, 2025 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (M) has an essential role in the virus lifecycle and, accordingly, it is a target for ... Read more

June 3, 2025

Calculation of COVID-19 disease burden using Monte Carlo simulation with dynamic disability weights and analysis of transmission characteristics.

Coronavirus Literature

Publication date: Jun 02, 2025 Disability Weights (DWs) are crucial for assessing disease burden guiding public health decision-making. For emerging health threats such as COVID-19, the absence of relevant survey ... Read more

June 3, 2025

Characteristics and predictors of mortality among infants and toddlers hospitalized with tuberculosis: a ten-year case series study in Sichuan, China.

Tuberculosis Literature

Publication date: Jun 02, 2025 Research on tuberculosis (TB) in infants and toddlers is limited in China. This study aims to describe the epidemiology of TB in this age group ... Read more