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March 24, 2025March 24, 2025

Exosome-based therapeutics: Advancing drug delivery for neurodegenerative diseases.

Publication date: Mar 21, 2025 Neurodegenerative disorders include Parkinson’s disease, spinal cord injury, multiple sclerosis and Alzheimer’s disease, cause gradual neuronal loss, protein misfolding, and accumulation, resulting in severe cognitive ... Read more

March 22, 2025March 22, 2025

Assessing the consistency of FIB-4, APRI, and GPR in evaluating significant liver fibrosis and cirrhosis in COVID-19 patients with concurrent liver diseases.

Coronavirus Literature

Publication date: Mar 20, 2025 This study investigated the consistency of the FIB-4, APRI, and GPR indices in assessing significant liver fibrosis and cirrhosis in patients with Coronavirus Disease 2019(COVID-19) ... Read more

March 22, 2025March 22, 2025

In vitro activation of anti-cancer gene expression by delivery of CRISPR/dCas9 ribonucleoproteins to suppress glioblastoma.

Melanoma Literature

Publication date: Mar 19, 2025 Cancer has been a leading cause of death for decades. While many anti-cancer drugs exist, precisely targeting malignant cells is crucial for successful tumor treatment. ... Read more

March 22, 2025March 22, 2025

Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo.

Parkinson's Disease Literature

Publication date: Mar 20, 2025 Cell-type-specific regulatory elements such as enhancers can direct expression of recombinant adeno-associated viruses (AAVs) to specific cell types, but this approach is limited by the ... Read more

March 22, 2025March 22, 2025

Methadone patient access to collaborative treatment (MPACT): Protocol for a pilot and a randomized controlled trial to establish feasibility of adoption and impact on methadone treatment delivery and patient outcomes.

Coronavirus Literature

Publication date: Mar 18, 2025 Access to methadone treatment can reduce opioid overdose death by up to 60%, but U. S. patient outcomes are suboptimal. Federally-allowed methadone treatment accommodations during ... Read more

March 22, 2025March 22, 2025

Methadone patient access to collaborative treatment (MPACT): Protocol for a pilot and a randomized controlled trial to establish feasibility of adoption and impact on methadone treatment delivery and patient outcomes.

Coronavirus Literature

March 22, 2025March 22, 2025

Costs of delivering COVID-19 vaccine in Botswana during the height of the pandemic: a retrospective study.

Coronavirus Literature

Publication date: Mar 19, 2025 The development, distribution and delivery of COVID-19 vaccines following the outbreak of the global coronavirus pandemic in February 2020 is the largest global immunization action ... Read more

March 22, 2025March 22, 2025

Costs of delivering COVID-19 vaccine in Botswana during the height of the pandemic: a retrospective study.

Coronavirus Literature

March 20, 2025March 20, 2025

Reducing Mental Health Stigma in the Workplace: A Meta-Analysis of The Working Mind Program in Virtual Delivery Format: Réduire la stigmatisation en milieu de travail : Une méta-analyse du programme L’esprit au travail en format virtuel.

Coronavirus Literature

Publication date: Mar 19, 2025 BackgroundMental health stigma in the workplace has been widely recognized, and workplace programs have been created to improve self-awareness and resiliency, while decreasing stigma. Prior ... Read more

March 20, 2025March 20, 2025

Investigation of the improvement of swallowing function with low-frequency pulse waves or interference waves delivered via cervical electrical stimulation in patients with Parkinson’s disease: A randomized controlled study protocol.

Parkinson's Disease Literature

Publication date: Apr 01, 2025 Parkinson’s disease (PD) is associated with a high rate of swallowing dysfunction, which may lead to aspiration pneumonia. This randomized controlled trial aims to investigate ... Read more