Search Results for: Metastasis

January 18, 2020

Accuracy of The Cancer Genome Atlas Classification vs American Joint Committee on Cancer Classification for Prediction of Metastasis in Patients With Uveal Melanoma.

Melanoma Literature

Publication date: Jan 16, 2020 The Cancer Genome Atlas (TCGA) classification is a newly emerging method for prediction of uveal melanoma (UM)-related metastasis and death. Limited information is available regarding ... Read more

January 18, 2020January 18, 2020

Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis.

Melanoma Literature

Publication date: Jan 16, 2020 Cutaneous malignant melanoma is an aggressive cancer of melanocytes with a strong propensity to metastasize. We posit that melanoma cells acquire metastatic capability by adopting ... Read more

January 18, 2020

Steroid receptor RNA activator (SRA), a long noncoding RNA, activates p38, facilitates epithelial mesenchymal transformation, and experimental melanoma metastasis.

Melanoma Literature

Publication date: Jan 13, 2020 Melanoma metastasis signals dismal prognosis even with current checkpoint inhibitors. Long noncoding RNAs (lncRNAs) regulate dynamic metastasis in several cancers, including melanoma. We become interested ... Read more

January 16, 2020January 16, 2020

Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis.

Melanoma Literature

Publication date: Jan 13, 2020 Metastasis is the primary cause of death of cancer patients. Dissecting mechanisms governing metastatic spread may uncover important tumor biology and/or yield promising therapeutic insights. ... Read more

January 3, 2020

Association of Partial Chromosome 3 Deletion in Uveal Melanomas With Metastasis-Free Survival.

Melanoma Literature

Publication date: Jan 02, 2020 Studies on uveal melanomas (UMs) have demonstrated the prognostic value of 8q gain and monosomy 3, but the prognosis of UMs with partial deletion of ... Read more

January 2, 2020January 2, 2020

The challenge of classifying metastatic cell properties by molecular profiling exemplified with cutaneous melanoma cells and their cerebral metastasis from patient derived mouse xenografts.

Melanoma Literature

Publication date: Dec 31, 2019 The prediction of metastatic properties from molecular analyses still poses a major challenge. Here we aimed at the classification of metastasis-related cell properties by proteome ... Read more

December 31, 2019December 31, 2019

Accumulation of CD103 CD8 T cells in a cutaneous melanoma micrometastasis.

Melanoma Literature

Publication date: Oct 24, 2019 The immune system can halt cancer progression by suppressing outgrowth of clinically occult micrometastases in a state of cancer-immune equilibrium. Cutaneous melanoma provides a unique ... Read more

December 25, 2019

Siglec1-expressing subcapsular sinus macrophages provide soil for melanoma lymph node metastasis.

Melanoma Literature

Publication date: Dec 24, 2019 Lymph nodes (LNs) are a common site of metastasis in solid cancers, and cutaneous melanomas show inherent properties of LN colonization. However, interactions between LN ... Read more

December 21, 2019

Bioengineering Bacterial Vesicle-Coated Polymeric Nanomedicine for Enhanced Cancer Immunotherapy and Metastasis Prevention.

Melanoma Literature

Publication date: Dec 20, 2019 We herein propose a bioengineering approach where bacterial outer membrane vesicles (OMVs) were coated on drug-loaded polymeric micelles to generate an innovative nanomedicine for effective ... Read more

December 19, 2019

Mitochondrial haplotype of the host stromal microenvironment alters metastasis in a non-cell autonomous manner.

Melanoma Literature

Publication date: Dec 17, 2019 Mitochondria contribute to tumor growth through multiple metabolic pathways, regulation of extracellular pH, calcium signaling, and apoptosis. Using the Mitochondrial Nuclear Exchange (MNX) mouse models, ... Read more