Search Results for: Methionine

June 1, 2019June 1, 2019

Association between polymorphisms of a folate – homocysteine – methionine – SAM metabolising enzyme gene and multiple sclerosis in a Polish population.

Publication date: May 30, 2019 Multiple sclerosis (MS) is a chronic inflammatory, autoimmune disease with still unknown etiology. The main initial mechanism of demyelination and injury to the central nervous ... Read more

April 19, 2019April 19, 2019

Usefulness of [C] Methionine PET in the Differentiation of Tumefactive Multiple Sclerosis from High Grade Astrocytoma.

Multiple Sclerosis Literature

Publication date: Apr 17, 2019 Tumefactive multiple sclerosis (tumefactive MS) is an atypical variant of MS characterized by a large isolated demyelinating lesion. Because tumefactive MS mimics high grade astrocytoma ... Read more

January 11, 2019January 11, 2019

Methionine Antagonizes para-Aminosalicylic Acid Activity via Affecting Folate Precursor Biosynthesis in Mycobacterium tuberculosis.

Tuberculosis Literature

Publication date: May 13, 2018 para-Aminosalicylic acid (PAS) is a second-line anti-tubercular drug that is used for the treatment of drug-resistant tuberculosis (TB). PAS efficacy in the treatment of TB ... Read more

November 15, 2018November 15, 2018

1,25-Dihydroxyvitamin D increases the methionine cycle, CD4 T cell DNA methylation and HeliosFoxp3 T regulatory cells to reverse autoimmune neurodegenerative disease.

Multiple Sclerosis Literature

Publication date: Nov 15, 2018 We investigated how one calcitriol dose plus vitamin D reverses experimental autoimmune encephalomyelitis (EAE), a multiple sclerosis model. This protocol rapidly increased CD4 T cell ... Read more

August 17, 2018August 17, 2018

A frontal tumefactive demyelinating lesion mimicking glioblastoma differentiated by methionine positron emission tomography.

Multiple Sclerosis Literature

Publication date: Aug 13, 2018 Tumefactive demyelinating lesion (TDL) is often reported as a rare variation of multiple sclerosis (MS). TDL is difficult to diagnose solely by magnetic resonance imaging ... Read more

June 26, 2018June 26, 2018

Modulation of Dietary Methionine Intake Elicits Potent, yet Distinct, Anticancer Effects on Primary Versus Metastatic Tumors.

Melanoma Literature

Publication date: Jun 23, 2018 Methionine dependency describes the characteristic rapid in vitro death of most tumor cells in the absence of methionine. Combining chemotherapy with dietary methionine deprivation (MDD) ... Read more

November 16, 2019November 16, 2019

Study to Evaluate Safety and Daytime Sedation in Subjects With Parkinson’s Disease With Neuropsychiatric Symptoms Treated With Pimavanserin or Low-Dose Quetiapine

Parkinson's Disease News

Publication date: Nov 15, 2019 This is a pilot, hypothesis-generating study to explore the effects of pimavanserin and low-dose quetiapine in subjects with Parkinson’s disease with neuropsychiatric symptoms. Concepts Keywords ... Read more

November 15, 2019November 15, 2019

Patient and provider differences in the treatment of opioid-induced constipation: a qualitative study.

Opioids Literature

Publication date: Nov 12, 2019 Patients using opioids to treat chronic non-cancer pain often experience side effects that may affect health-related quality of life (HRQOL). These side effects include opioid-induced ... Read more

November 15, 2019November 15, 2019

Patient and provider differences in the treatment of opioid-induced constipation: a qualitative study.

Opioids Literature

November 15, 2019November 15, 2019

An integrative methodology based on protein-protein interaction networks for identification and functional annotation of disease-relevant genes applied to channelopathies.

Precision Medicine Literature

Publication date: Nov 12, 2019 Biologically data-driven networks have become powerful analytical tools that handle massive, heterogeneous datasets generated from biomedical fields. Protein-protein interaction networks can identify the most relevant ... Read more