Search Results for: Methionine

June 1, 2019June 1, 2019

Association between polymorphisms of a folate – homocysteine – methionine – SAM metabolising enzyme gene and multiple sclerosis in a Polish population.

Publication date: May 30, 2019 Multiple sclerosis (MS) is a chronic inflammatory, autoimmune disease with still unknown etiology. The main initial mechanism of demyelination and injury to the central nervous ... Read more

April 19, 2019April 19, 2019

Usefulness of [C] Methionine PET in the Differentiation of Tumefactive Multiple Sclerosis from High Grade Astrocytoma.

Multiple Sclerosis Literature

Publication date: Apr 17, 2019 Tumefactive multiple sclerosis (tumefactive MS) is an atypical variant of MS characterized by a large isolated demyelinating lesion. Because tumefactive MS mimics high grade astrocytoma ... Read more

January 11, 2019January 11, 2019

Methionine Antagonizes para-Aminosalicylic Acid Activity via Affecting Folate Precursor Biosynthesis in Mycobacterium tuberculosis.

Tuberculosis Literature

Publication date: May 13, 2018 para-Aminosalicylic acid (PAS) is a second-line anti-tubercular drug that is used for the treatment of drug-resistant tuberculosis (TB). PAS efficacy in the treatment of TB ... Read more

November 15, 2018November 15, 2018

1,25-Dihydroxyvitamin D increases the methionine cycle, CD4 T cell DNA methylation and HeliosFoxp3 T regulatory cells to reverse autoimmune neurodegenerative disease.

Multiple Sclerosis Literature

Publication date: Nov 15, 2018 We investigated how one calcitriol dose plus vitamin D reverses experimental autoimmune encephalomyelitis (EAE), a multiple sclerosis model. This protocol rapidly increased CD4 T cell ... Read more

August 17, 2018August 17, 2018

A frontal tumefactive demyelinating lesion mimicking glioblastoma differentiated by methionine positron emission tomography.

Multiple Sclerosis Literature

Publication date: Aug 13, 2018 Tumefactive demyelinating lesion (TDL) is often reported as a rare variation of multiple sclerosis (MS). TDL is difficult to diagnose solely by magnetic resonance imaging ... Read more

June 26, 2018June 26, 2018

Modulation of Dietary Methionine Intake Elicits Potent, yet Distinct, Anticancer Effects on Primary Versus Metastatic Tumors.

Melanoma Literature

Publication date: Jun 23, 2018 Methionine dependency describes the characteristic rapid in vitro death of most tumor cells in the absence of methionine. Combining chemotherapy with dietary methionine deprivation (MDD) ... Read more

July 17, 2019July 17, 2019

Transgenerational transfer of gene-modified T cells.

Melanoma Literature

Publication date: Jul 15, 2019 Tumor immunotherapy using gene-modified T cells has already met with considerable success in the treatment of metastatic melanoma and B cell lymphoma. With improving patient ... Read more

July 16, 2019July 16, 2019

A prospective, observational study on conversion of clinically isolated syndrome to multiple sclerosis during 4-year period (MS NEO study) in Taiwan.

Multiple Sclerosis Literature

Publication date: Aug 01, 2018 CIS to MS conversion rates vary depending on population cohorts, initial manifestations, and durations of follow-up. To investigate conversion rate of patients from CIS to ... Read more

July 14, 2019July 14, 2019

Peripheral Expression of Mutant Huntingtin is a Critical Determinant of Weight Loss and Metabolic Disturbances in Huntington’s Disease.

Huntington's Disease Literature

Publication date: Jul 12, 2019 Deteriorating weight loss in patients with Huntington’s disease (HD) is a complicated peripheral manifestation and the cause remains poorly understood. Studies suggest that body weight ... Read more

July 12, 2019July 12, 2019

Pharmacokinetics and tolerability of inhaled levodopa from a new dry-powder inhaler in patients with Parkinson’s disease.

Parkinson's Disease Literature

Publication date: Mar 28, 2019 Inhaled levodopa may quickly resolve off periods in Parkinson’s disease. Our aim was to determine the pharmacokinetics and tolerability of a new levodopa dry-powder inhaler. ... Read more