Search Results for: Methionine

June 1, 2019June 1, 2019

Association between polymorphisms of a folate – homocysteine – methionine – SAM metabolising enzyme gene and multiple sclerosis in a Polish population.

Publication date: May 30, 2019 Multiple sclerosis (MS) is a chronic inflammatory, autoimmune disease with still unknown etiology. The main initial mechanism of demyelination and injury to the central nervous ... Read more

April 19, 2019April 19, 2019

Usefulness of [C] Methionine PET in the Differentiation of Tumefactive Multiple Sclerosis from High Grade Astrocytoma.

Multiple Sclerosis Literature

Publication date: Apr 17, 2019 Tumefactive multiple sclerosis (tumefactive MS) is an atypical variant of MS characterized by a large isolated demyelinating lesion. Because tumefactive MS mimics high grade astrocytoma ... Read more

January 11, 2019January 11, 2019

Methionine Antagonizes para-Aminosalicylic Acid Activity via Affecting Folate Precursor Biosynthesis in Mycobacterium tuberculosis.

Tuberculosis Literature

Publication date: May 13, 2018 para-Aminosalicylic acid (PAS) is a second-line anti-tubercular drug that is used for the treatment of drug-resistant tuberculosis (TB). PAS efficacy in the treatment of TB ... Read more

November 15, 2018November 15, 2018

1,25-Dihydroxyvitamin D increases the methionine cycle, CD4 T cell DNA methylation and HeliosFoxp3 T regulatory cells to reverse autoimmune neurodegenerative disease.

Multiple Sclerosis Literature

Publication date: Nov 15, 2018 We investigated how one calcitriol dose plus vitamin D reverses experimental autoimmune encephalomyelitis (EAE), a multiple sclerosis model. This protocol rapidly increased CD4 T cell ... Read more

August 17, 2018August 17, 2018

A frontal tumefactive demyelinating lesion mimicking glioblastoma differentiated by methionine positron emission tomography.

Multiple Sclerosis Literature

Publication date: Aug 13, 2018 Tumefactive demyelinating lesion (TDL) is often reported as a rare variation of multiple sclerosis (MS). TDL is difficult to diagnose solely by magnetic resonance imaging ... Read more

June 26, 2018June 26, 2018

Modulation of Dietary Methionine Intake Elicits Potent, yet Distinct, Anticancer Effects on Primary Versus Metastatic Tumors.

Melanoma Literature

Publication date: Jun 23, 2018 Methionine dependency describes the characteristic rapid in vitro death of most tumor cells in the absence of methionine. Combining chemotherapy with dietary methionine deprivation (MDD) ... Read more

January 24, 2020January 24, 2020

8 Week Multi-site Study of MYDAYIS® for Bipolar Depression

Major Depressive Disorder News

Publication date: Jan 22, 2020 This protocol is a Phase 2 multi-site study which aims to evaluate the safety and effectiveness of MYDAYIS® as adjunctive therapy for adults with bipolar ... Read more

January 24, 2020January 24, 2020

Efficacy of Digital Cognitive Behavioral Therapy for the Treatment of Insomnia Symptoms Among Pregnant Women: A Randomized Clinical Trial.

Major Depressive Disorder Literature

Publication date: Jan 22, 2020 Despite the prevalence and adverse consequences of prenatal insomnia, a paucity of research is available regarding interventions to improve insomnia symptoms during pregnancy. To test ... Read more

January 24, 2020

An integrated meta-analysis of peripheral blood metabolites and biological functions in major depressive disorder.

Major Depressive Disorder Literature

Publication date: Jan 20, 2020 Major depressive disorder (MDD) is a serious mental illness, characterized by high morbidity, which has increased in recent decades. However, the molecular mechanisms underlying MDD ... Read more

January 24, 2020January 24, 2020

Astrocyte Support for Oligodendrocyte Differentiation can be Conveyed via Extracellular Vesicles but Diminishes with Age.

Multiple Sclerosis Literature

Publication date: Jan 21, 2020 The aging brain is associated with significant changes in physiology that alter the tissue microenvironment of the central nervous system (CNS). In the aged CNS, ... Read more