Search Results for: Microenvironment

January 11, 2025January 11, 2025

PD-L1, PD-1, and CTLA-4 mRNA In Situ Expression by Canine Oral Melanoma Cells and Immune Cells of the Tumour Microenvironment.

Melanoma Literature

Publication date: Jan 09, 2025 Canine oral melanoma (OM) exhibits poor prognosis and limited treatment options. The success of immune checkpoint inhibitors (ICIs) in human melanoma has driven interest in ... Read more

January 10, 2025January 10, 2025

Size-specific clonidine-loaded liposomes: Advancing melanoma microenvironment suppression with safety and precision.

Melanoma Literature

Publication date: Jan 08, 2025 The immunosuppressive tumor microenvironment (TME) plays a crucial role in the progression and treatment resistance of melanoma. Modulating the TME is thus a key strategy ... Read more

January 3, 2025January 3, 2025

Unveiling the role of ACTL6A in uveal melanoma metastasis and immune microenvironment.

Melanoma Literature

Publication date: Jan 01, 2025 To predict and evaluate the possible mechanisms and clinical value of ACTL6A in the prognosis and development of UM. Bioinformatics analyze the relationship between ACTL6A ... Read more

December 29, 2024December 29, 2024

Prognostic value and immune infiltration of a tumor microenvironment-related PTPN6 in metastatic melanoma.

Melanoma Literature

Publication date: Dec 28, 2024 Cutaneous melanoma is one of the most invasive and lethal skin malignant tumors. Compared to primary melanoma, metastatic melanoma (MM) presents poorer treatment outcomes and ... Read more

December 27, 2024December 27, 2024

Diversity of the immune microenvironment and response to checkpoint inhibitor immunotherapy in mucosal melanoma.

Melanoma Literature

Publication date: Nov 08, 2024 Mucosal melanoma (MucM) is a rare cancer with a poor prognosis and low response rate to immune checkpoint inhibition (ICI) compared with cutaneous melanoma (CM). ... Read more

December 25, 2024December 25, 2024

Induction of cell death in malignant cells and regulatory T cells in the tumor microenvironment by targeting CD137.

Melanoma Literature

Publication date: Dec 01, 2025 Regulatory T cells (Tregs) contribute significantly to the immunosuppressive nature of the tumor microenvironment which is a main barrier for immunotherapies of solid cancers. Reducing ... Read more

December 8, 2024December 8, 2024

A size-switchable nanocluster remodels the immunosuppressive microenvironment of tumor and tumor-draining lymph nodes for improved cancer immunotherapy.

Melanoma Literature

Publication date: Apr 01, 2025 Remodeling the immunosuppressive tumor microenvironment (TME) by immunomodulators has been well studied in the past years. However, strategies that enable concurrent modulation of both the ... Read more

December 7, 2024December 7, 2024

The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication.

Tuberculosis Literature

Publication date: Dec 06, 2024 Severity of COVID-19 is affected by multiple factors; however, it is not understood how the inflammatory milieu of the lung at the time of SARS-CoV-2 ... Read more

December 5, 2024December 5, 2024

Single-cell profiling of acral melanoma infiltrating lymphocytes reveals a suppressive tumor microenvironment.

Melanoma Literature

Publication date: Dec 04, 2024 Acral lentiginous melanoma (ALM) is the most common melanoma subtype in non-Caucasians. Despite advances in cancer immunotherapy, current immune checkpoint inhibitors remain unsatisfactory for ALM. ... Read more

December 4, 2024December 4, 2024

A comprehensive pan-cancer analysis of SARS-CoV-2-related cancer malignancy: COVID-19 infection shapes a dynamic immune microenvironment and affects the prognosis.

Coronavirus Literature

Publication date: Nov 30, 2024 Concepts Keywords Cancer Affects Covid Cancer Malignancy Comprehensive Prognosis Cov Covid Dynamic Immune Infection Malignancy Microenvironment Pan Prognosis Related Sars Shapes Semantics Type Source Name ... Read more