Search Results for: Mitochondria

July 2, 2020July 2, 2020

Inflammation and Mitochondrial Dysfunction in Autism Spectrum Disorder.

Autism Literature

Publication date: Jun 27, 2020 Autism Spectrum Disorders (ASD) is a severe childhood psychiatric condition with an array of cognitive, language and social impairments that can significantly impact on family ... Read more

July 1, 2020July 1, 2020

Targeting mitochondrial calcium pathways as a potential treatment against Parkinson’s disease.

Parkinson's Disease Literature

Publication date: Jul 01, 2020 Parkinson’s disease (PD) is a major health problem worldwide affecting millions of people and is a result of neurodegeneration in a small part of the ... Read more

June 29, 2020June 29, 2020

Overexpression of PGC-1α influences the mitochondrial unfolded protein response (mtUPR) induced by MPP in human SH-SY5Y neuroblastoma cells.

Parkinson's Disease Literature

Publication date: Jun 26, 2020 Parkinson’s disease (PD) is a common dyskinesia disease, the mitochondrial unfolded protein response (mtUPR) may be directly or indirectly involved in the occurrence and development ... Read more

June 26, 2020June 26, 2020

Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson’s disease through mitochondrial dysfunction.

Parkinson's Disease Literature

Publication date: Jun 24, 2020 Parkinson’s disease (PD) is a neurodegenerative disorder featuring progressive loss of midbrain dopaminergic (DA) neurons that leads to motor symptoms. The etiology and pathogenesis of ... Read more

June 25, 2020June 25, 2020

Mitochondria and Microbiota dysfunction in COVID-19 pathogenesis.

Coronavirus Literature

Publication date: Jun 20, 2020 The COVID-19 pandemic caused by the coronavirus (SARS-CoV-2) has taken the world by surprise into a major crisis of overwhelming morbidity and mortality. This highly ... Read more

June 25, 2020June 25, 2020

Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis.

Multiple Sclerosis Literature

Publication date: Jun 22, 2020 Axonal loss is the key pathological substrate of neurological disability in demyelinating disorders, including multiple sclerosis (MS). However, the consequences of demyelination on neuronal and ... Read more

June 23, 2020June 23, 2020

The Role of Genetic Sex and Mitochondria in Response to COVID-19 Infection.

Coronavirus Literature

Publication date: Jun 19, 2020 The difference between the female and male immune response to COVID-19 infection, and infections in general, is multifactorial. The well-known determiners of the immune response, ... Read more

June 23, 2020June 23, 2020

The Impact of Mitochondrial Dysfunction on Dopaminergic Neurons in the Olfactory Bulb and Odor Detection.

Parkinson's Disease Literature

Publication date: Jun 20, 2020 Understanding non-motor symptoms of Parkinson’s disease is important in order to unravel the underlying molecular mechanisms of the disease. Olfactory dysfunction is an early stage, ... Read more

June 22, 2020June 22, 2020

Targeting mitochondria in melanoma: interplay between MAPK signaling pathway and mitochondrial dynamics.

Melanoma Literature

Publication date: Jun 17, 2020 Melanoma is a malignant proliferative disease originated in melanocytes, characterized by high metastatic activity and by the activation of oncogenes, such as B-RAF (40-60% of ... Read more

June 21, 2020June 21, 2020

Enhancing mitochondrial activity in neurons protects against neurodegeneration in CNS inflammation

Multiple Sclerosis News

Publication date: Jun 19, 2020 Central nervous system (CNS) inflammation in multiple sclerosis (MS) drives neuro-axonal loss resulting in irreversible disability. While transcripts of mitochondrial genes are strongly suppressed in ... Read more