Search Results for: Molecular

January 18, 2025January 18, 2025

Thermally Triggered Double Emulsion-Integrated Hydrogel Microparticles for Multiplexed Molecular Diagnostics.

Publication date: Jan 16, 2025 During the COVID-19 pandemic, reverse transcription-quantitative polymerase chain reaction (RT-qPCR) has been recognized as the most reliable diagnostic tool. However, there is a need to ... Read more

January 18, 2025January 18, 2025

Integrating network pharmacology with molecular docking and dynamics to uncover therapeutic targets and signaling mechanisms of vitamin D3 in Parkinson’s disease.

Parkinson's Disease Literature

Publication date: Jan 17, 2025 Parkinson’s disease (PD) is a chronic neurodegenerative disorder marked by dopaminergic neuron degeneration in the substantia nigra. Emerging evidence suggests vitamin D3 (VD) plays a ... Read more

January 17, 2025January 17, 2025

Systematic Molecular Influenza A/B Screening Upon Hospital Admission in Belgium, January-April 2022: Positivity Ratios and Viral Loads According to Symptomatology, Age, and Vaccination Status.

Coronavirus Literature

Publication date: Jan 01, 2025 Three hospitals implemented molecular point-of-care tests (POCTs) to screen patients for SARS-CoV-2 infection upon admission during the 2021/2022 influenza season, which in Belgium lasted from ... Read more

January 17, 2025January 17, 2025

Synthesis, biological evaluation and molecular docking studies of flavonol-3-O-β-D-glycoside as a potential inhibitor of SARS-CoV-2 main protease (3CLpro) in drug development for COVID-19.

Coronavirus Literature

Publication date: Jan 14, 2025 The COVID-19 pandemic began in March 2020 and has affected many countries and infected over a million people. It has had a serious impact on ... Read more

January 16, 2025January 16, 2025

Molecular switch of the dendrite-to-spine transport of TDP-43/FMRP-bound neuronal mRNAs and its impairment in ASD.

Autism Literature

Publication date: Jan 15, 2025 Regulation of messenger RNA (mRNA) transport and translation in neurons is essential for dendritic plasticity and learning/memory development. The trafficking of mRNAs along the hippocampal ... Read more

January 16, 2025January 16, 2025

Rapid and comprehensive detection of viral antibodies and nucleic acids via an acoustofluidic integrated molecular diagnostics chip: AIMDx.

Coronavirus Literature

Publication date: Jan 17, 2025 Precise and rapid disease detection is critical for controlling infectious diseases like COVID-19. Current technologies struggle to simultaneously identify viral RNAs and host immune antibodies ... Read more

January 15, 2025January 15, 2025

Congenital melanocytic neoplasms: clinical, histopathological and recent molecular developments.

Melanoma Literature

Publication date: Jan 15, 2025 Concepts Keywords Clinical Congenital nevus Congenital Neurocutaneous melanocytosis Histopathological Pediatric melanocytic neoplasm Molecular Pediatric melanoma Recent Semantics Type Source Name disease MESH neoplasms disease MESH ... Read more

January 15, 2025January 15, 2025

Molecular mechanisms of the GABA type A receptor function.

Autism Literature

Publication date: Jan 14, 2025 The GABA type A receptor (GABAR) belongs to the family of pentameric ligand-gated ion channels and plays a key role in inhibition in adult mammalian ... Read more

January 13, 2025January 13, 2025

Introduction of molecular point-of-care testing for SARS-CoV-2 in a triage unit of a large maternity hospital: An evaluation of staff experiences.

Coronavirus Literature

Publication date: Jan 10, 2025 Recent advances in the development of rapid SARS-CoV-2 point of care (POC) testing provided an opportunity to aid clinical decision making in front-line healthcare settings. ... Read more

January 13, 2025January 13, 2025

Molecular insights into Parkinson’s disease and type 2 diabetes mellitus: Metformin’s role and genetic pathways explored.

Parkinson's Disease Literature

Publication date: Jan 10, 2025 Background To explore whether there is a bidirectional relationship between Parkinson’s disease (PD) and type 2 diabetes mellitus (T2DM), study the common pathogenic mechanisms, screen ... Read more