Search Results for: Morphine

November 9, 2019November 9, 2019

Staccato Apomorphine Multi-dose PK and PD in Patients With Parkinson’s Disease

Publication date: Nov 08, 2019 This study will be conducted in subjects with established Parkinson’s disease in 2 parts. Part A will examine the tolerability, safety, and pharmacokinetics of AZ-009 ... Read more

November 2, 2019November 2, 2019

Intravenous Acetaminophen and Morphine Versus Intravenous Morphine Alone for Acute Pain in the Emergency Department

Opioids News

Publication date: Nov 01, 2019 In emergency medicine, acute pain is a common reason for consultation. It is recommended that patients in moderate to severe pain should receive a combination ... Read more

October 24, 2019October 24, 2019

Movapo® (apomorphine hydrochloride) for Patients with Advanced Parkinson’s Disease Now Reimbursed in Most Canadian Provinces

Parkinson's Disease News

Publication date: Oct 24, 2019 MONTREAL , Oct. 23, 2019 /PRNewswire/ — Paladin Labs Inc. , a subsidiary of Endo International plc (NASDAQ: ENDP), today announced that patients diagnosed with ... Read more

October 19, 2019October 19, 2019

Morphine decreases the function of primary human natural killer cells by both TLR4 and opioid receptor signaling.

Opioids Literature

Publication date: Oct 15, 2019 Opioids are commonly used to provide analgesia for cancer pain, and functional opioid receptors have been identified on natural killer (NK) cells, the lymphocytes responsible ... Read more

October 17, 2019October 17, 2019

Morphine activates blast-phase chronic myeloid leukemia cells and alleviates the effects of tyrosine kinase inhibitors.

Opioids Literature

Publication date: Oct 12, 2019 Morphine is an opioid analgesic drug routinely used in the postoperative period for pain management in cancer patients. In this work, we analyzed the effects ... Read more

October 17, 2019October 17, 2019

Electronic Health Record (EHR)-embedded Decision Support Platform for Morphine Precision Dosing in Neonates.

Opioids Literature

Publication date: Oct 16, 2019 Morphine is the opioid most commonly used for neonatal pain management. In intravenous form, it is administered as continuous infusions and intermittent injections, mostly based ... Read more

October 5, 2019October 5, 2019

A Relation of Morphine-induced Itch and Pain Processing

Opioids News

Publication date: Oct 04, 2019 In This experiment, the investigators would like to test the two following hypotheses regarding the mechanisms by which opioids cause itch: 1. Opioids cause itch ... Read more

September 28, 2019September 28, 2019

Understanding the Risks and Side Effects of Using Morphine

Opioids News

Publication date: Sep 28, 2019 During the American Civil War, this side effect became more widely known, as many soldiers developed morphine dependence. Morphine and other opioids have serious side ... Read more

$Post-market, Randomized, Controlled, Prospective Study Evaluating Intrathecal Morphine (IT) Versus Conventional Medical Management (CMM) in the Non-cancer, Refractory, Chronic Pain Population (PROSPER)$

September 20, 2019September 20, 2019

Post-market, Randomized, Controlled, Prospective Study Evaluating Intrathecal Morphine (IT) Versus Conventional Medical Management (CMM) in the Non-cancer, Refractory, Chronic Pain Population (PROSPER)

Opioids News

Publication date: Sep 19, 2019 This study is being conducted to compare intrathecal morphine using the commercially available intrathecal drug delivery systems (IDDS), and conventional medical management (CMM) in subjects ... Read more

September 4, 2019September 4, 2019

Phosphorylation of unique C-terminal sites of the mu-opioid receptor variants 1B2 and 1C1 influences their Gs association following chronic morphine.

Opioids Literature

Publication date: Sep 03, 2019 We recently demonstrated in rat spinal cord that a regimen of escalating doses of systemic morphine, analogous to regimens used clinically for chronic pain management, ... Read more