Search Results for: Mutation

October 12, 2024October 12, 2024

An Unexpected Finding of a PTPN11 Germline Mutation in a Patient With a Melanocytic Lesion With a Somatic MAP2K1 Mutation. Coincidence or Not?

Melanoma Literature

Publication date: Oct 11, 2024 Melanocytic tumors are a diverse group of lesions and are traditionally classified based on a combination of clinical presentation as well as histological examination. More ... Read more

October 12, 2024October 12, 2024

An Unexpected Finding of a PTPN11 Germline Mutation in a Patient With a Melanocytic Lesion With a Somatic MAP2K1 Mutation. Coincidence or Not?

Melanoma Literature

October 12, 2024October 12, 2024

Dopamine and cortical iPSC-derived neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction: implications for protein deposition versus selective cell loss

Parkinson's Disease News

Publication date: Oct 10, 2024 Background: Mutations causing Parkinson’s disease (PD) give diverse pathological phenotypes whose cellular correlates remain to be determined. For example, those with PRKN loss of function ... Read more

October 11, 2024October 11, 2024

The evaluation of SARS-CoV-2 mutations at the early stage of the pandemic in Istanbul population.

Coronavirus Literature

Publication date: Oct 10, 2024 Determination of SARS-CoV-2 variant is significant to prevent the spreads of COVID-19 disease. We aimed to evaluate the variants of SARS-CoV-2 rate in positive patients ... Read more

October 11, 2024October 11, 2024

The evaluation of SARS-CoV-2 mutations at the early stage of the pandemic in Istanbul population.

Coronavirus Literature

October 11, 2024October 11, 2024

Loss of mitochondrial Ca response and CaMKII/ERK activation by LRRK2 mutation correlate with impaired depolarization-induced mitophagy.

Parkinson's Disease Literature

Publication date: Oct 10, 2024 Open Access PDF Concepts Keywords Abolished Calcium-dependent pathways Atp Cellular stress response Calcium LRRK2 mutation Neurodegeneration Mitochondrial dysfunction Seahorse Mitophagy NCLX Parkinson disease Semantics Type ... Read more

October 9, 2024October 9, 2024

A prediction of mutations in infectious viruses using artificial intelligence.

Coronavirus Literature

Publication date: Oct 08, 2024 Many subtypes of SARS-CoV-2 have emerged since its early stages, with mutations showing regional and racial differences. These mutations significantly affected the infectivity and severity ... Read more

October 9, 2024October 9, 2024

Viral coexistence and insertional mutations in the ORF8 region of SARS-CoV-2: A possible mechanism of nucleotide insertion.

Coronavirus Literature

Publication date: Oct 05, 2024 The virus obtained from a swab sample ID: S66 in Hiroshima was reported to have a single T-base insertion in the ORF8 coding region. However, ... Read more

October 9, 2024October 9, 2024

Viral coexistence and insertional mutations in the ORF8 region of SARS-CoV-2: A possible mechanism of nucleotide insertion.

Coronavirus Literature

Publication date: Oct 05, 2024 The virus obtained from a swab sample ID: S66 in Hiroshima was reported to have a single T-base insertion in the ORF8 coding region. However, ... Read more

October 9, 2024October 9, 2024

Viral coexistence and insertional mutations in the ORF8 region of SARS-CoV-2: A possible mechanism of nucleotide insertion.

Coronavirus Literature

Publication date: Oct 05, 2024 The virus obtained from a swab sample ID: S66 in Hiroshima was reported to have a single T-base insertion in the ORF8 coding region. However, ... Read more