Search Results for: NMDA receptor

November 22, 2019November 22, 2019

Potentiation of morphine-induced antinociception by harmaline: involvement of μ-opioid and ventral tegmental area NMDA receptors.

Opioids Literature

Publication date: Nov 18, 2019 Morphine is one of the most well-known and potent analgesic agents; however, it can also induce various side effects. Thus, finding drugs and mechanisms which ... Read more

April 25, 2019April 25, 2019

Mitogen-activated protein kinase signaling mediates opioid-induced presynaptic NMDA receptor activation and analgesic tolerance.

Opioids Literature

Publication date: Jan 01, 2019 Opioid-induced hyperalgesia and analgesic tolerance can lead to dose escalation and inadequate pain treatment with μ-opioid receptor agonists. Opioids cause tonic activation of glutamate NMDA ... Read more

August 2, 2018August 2, 2018

SAP97-mediated rescue of NMDA receptor surface distribution in a neuronal model of Huntington’s Disease.

Huntington's Disease Literature

Publication date: Aug 01, 2018 Huntington’s disease (HD) is a genetic neurodegenerative disorder caused by an expansion of the CAG repeat tract in the HTT gene, leading to motor, cognitive, ... Read more

May 25, 2018May 25, 2018

Expression of NMDA receptor subunits in human blood lymphocytes: A peripheral biomarker in online computer game addiction.

Opioids Literature

Publication date: May 23, 2018 Background and aims Repeated performance of some behaviors such as playing computer games could result in addiction. The NMDA receptor is critically involved in the ... Read more

May 18, 2018May 18, 2018

NMDA receptor subunits change in the prefrontal cortex of pure-opioid and multi-drug abusers: a post-mortem study.

Opioids Literature

Publication date: May 16, 2018 Addiction is a chronic relapsing disorder and is one of the most important issues in the world. Changing the level of neurotransmitters and the activities ... Read more

March 25, 2018March 25, 2018

Genetic predisposition in anti-LGI1 and anti-NMDA receptor encephalitis.

Multiple Sclerosis Literature

Publication date: Mar 23, 2018 We performed a genome-wide-association study in 1,194 controls and 150 patients with anti-N-methyl-D-aspartate receptor (anti-NMDAR, n=96) or anti-leucine-rich glioma-inactivated1 (anti-LGI1, n=54) autoimmune encephalitis. Anti-LGI1 encephalitis ... Read more

November 8, 2019November 8, 2019

Pharmacokinetic and pharmacodynamic considerations for NMDA-receptor antagonist ketamine in the treatment of chronic neuropathic pain: an update of the most recent literature.

Opioids Literature

Publication date: Nov 06, 2019 Introduction: Chronic neuropathic pain (NP) is an incapacitating illness caused by alesion of the somatosensory nervous system and is associated with several disease or syndromes. ... Read more

February 21, 2018February 21, 2018

NMDAR (N-methyl-D-aspartate receptor) encephalitis in a patient with MS (multiple sclerosis): a rare and challenging case.

Multiple Sclerosis Literature

Publication date: Feb 17, 2018 We present a rare case of N-methyl-D-aspartate receptor (NMDAR) encephalitis in a 41-year-old Caucasian woman, who initially presented with prominent neuropsychiatric symptoms on the background ... Read more

November 8, 2019November 8, 2019

Does kynurenic acid act on nicotinic receptors? An assessment of the evidence.

Huntington's Disease Literature

Publication date: Nov 06, 2019 As a major metabolite of kynurenine in the oxidative metabolism of tryptophan, kynurenic acid is of considerable biological and clinical importance as an endogenous antagonist ... Read more

July 18, 2019July 18, 2019

Cerebrospinal fluid light and heavy neurofilament level increased in anti-N-methyl-d-aspartate receptor encephalitis.

Multiple Sclerosis Literature

Publication date: Jul 17, 2019 Neurofilaments (Nf) are a series of highly specific scaffolding proteins of neurons. Neurofilament light chains (Nf-L) and the heavy one (Nf-H) are subunits of Nf, ... Read more