Search Results for: Nanoparticle

March 21, 2025March 21, 2025

Functionalized Cerium Oxide Nanoparticles Enhance Penetration into Melanoma Spheroids In Vivo through Angiogenesis.

Melanoma Literature

Publication date: Mar 20, 2025 Angiogenesis is a crucial step in tumor progression, including melanoma, making anti-angiogenic strategies a widely explored treatment approach. However, both innate and acquired resistance to ... Read more

March 21, 2025March 21, 2025

Effectiveness of Mycobacterium tuberculosis recombinant proteins-coated gold nanoparticles in improving the interferon-gamma release assay test.

Tuberculosis Literature

Publication date: Mar 01, 2025 Gold nanoparticles (GNPs) are chemically inert, have low toxicity, and are easy to modify and functionalize for the detection of many pathogens. They have excellent ... Read more

March 20, 2025March 20, 2025

Practical approach to development of GS-445124-loaded PLGA nanoparticles for the long-term treatment of feline infectious peritonitis caused by feline coronavirus infection.

Coronavirus Literature

Publication date: Mar 17, 2025 Feline infectious peritonitis virus (FIPV) caused by feline coronavirus (FCoV) infection leads to a high mortality rate when untreated. GS-441524, an antiviral agent effective against ... Read more

March 20, 2025March 20, 2025

The immunogenic potential of an optimized mRNA lipid nanoparticle formulation carrying sequences from virus and protozoan antigens.

Coronavirus Literature

Publication date: Mar 18, 2025 Lipid nanoparticles (LNP) are a safe and effective messenger RNA (mRNA) delivery system for vaccine applications, as shown by the COVID-19 mRNA vaccines. One of ... Read more

March 20, 2025March 20, 2025

Enhancing Chimeric Antigen Receptor T-Cell Generation via Microfluidic Mechanoporation and Lipid Nanoparticles.

Melanoma Literature

Publication date: Mar 19, 2025 Chimeric antigen receptor (CAR)-T cell therapy has revolutionized cancer treatment by engineering patients’ T cells to specifically target cancer cells. Traditional CAR-T cell manufacturing methods ... Read more

March 20, 2025March 20, 2025

Auranofin-loaded chitosan-lipid hybrid nanoparticle protects against the in-vitro/in-vivo model of Parkinson’s disease via modulation of GSK-3β/ Nrf2/HO-1 signaling.

Parkinson's Disease Literature

Publication date: Mar 17, 2025 Auranofin (AUF) is a gold-based compound that has demonstrated a wide range of biological effects, such as anti-inflammatory and antibacterial effects. However, the neuronal use ... Read more

March 20, 2025March 20, 2025

Poly(2-ethyl-2-oxazoline) (POx) as Poly(ethylene glycol) (PEG)-Lipid Substitute for Lipid Nanoparticle Formulations.

Coronavirus Literature

Publication date: Mar 19, 2025 Polyoxazolines have long been considered as promising alternatives to poly(ethylene glycol) (PEG) due to their comparable properties, in particular regarding their stealth effect toward the ... Read more

March 19, 2025March 19, 2025

New Insights on the Potential Role of Pyroptosis in Parkinson’s Neuropathology and Therapeutic Targeting of NLRP3 Inflammasome with Recent Advances in Nanoparticle-Based miRNA Therapeutics.

Parkinson's Disease Literature

Publication date: Mar 18, 2025 Parkinson’s disease (PD) is a widespread neurodegenerative disorder characterized by the gradual degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNc). This review ... Read more

March 19, 2025March 19, 2025

3D spheroid model reveals enhanced efficacy of mannose-decorated nanoparticles for TB treatment.

Tuberculosis Literature

Publication date: Mar 18, 2025 Tuberculosis (TB), caused by Mycobacterium tuberculosis remains a significant global health challenge aggravated by drug-resistant strains and prolonged treatment regimens. Innovative strategies to enhance treatment ... Read more

March 16, 2025March 16, 2025

Nanoparticles of natural product-derived medicines: Beyond the pandemic.

Coronavirus Literature

Publication date: Feb 28, 2025 This review explores the synergistic potential of natural products and nanotechnology for viral infections, highlighting key antiviral, immunomodulatory, and antioxidant properties to combat pandemics caused ... Read more