Search Results for: Nerve Injury

April 24, 2020April 24, 2020

4-PBA enhances autophagy by inhibiting endoplasmic reticulum stress in recombinant human beta nerve growth factor induced PC12 cells after mechanical injury via PI3K/AKT/mTOR signaling pathway.

Publication date: Mar 13, 2020 To investigate mechanism of endoplasmic reticulum (ER) stress-mediated autophagy in spinal cord injury (SCI). An in vitro model of spinal cord injury(SCI)was established by recombinant ... Read more

June 26, 2020June 26, 2020

Impact of Transcutaneous Vagal Nerve Stimulation on Stress Response in Major Depression

Major Depressive Disorder News

Publication date: Jun 25, 2020 This study will identify the sex-dependent impact of expiratory-gated transcutaneous vagus nerve stimulation (tVNS) on the modulation of the stress response circuitry and associated physiology ... Read more

June 1, 2020June 1, 2020

Study of retinal nerve fiber layer analysis using optical coherence tomography in different demyelinating diseases and its correlation with the severity of visual impairment.

Multiple Sclerosis Literature

Publication date: Jun 01, 2020 This purpose of this study was to find the association between severity of visual impairment and retinal nerve fiber layer (RNFL) thickness loss in different ... Read more

April 21, 2020April 21, 2020

Immunomodulation by dimethyl fumarate treatment improves mouse sciatic nerve regeneration.

Multiple Sclerosis Literature

Publication date: Apr 16, 2020 Traumatic injury to the peripheral nervous system (PNS) often generates sensorimotor deficits that impair the quality of life of the patient. The success of nerve ... Read more

February 20, 2020February 20, 2020

Transcutaneous Electrical Nerve Stimulation in Relieving Neuropathic Pain: Basic Mechanisms and Clinical Applications.

Multiple Sclerosis Literature

Publication date: Feb 18, 2020 Transcutaneous electrical nerve stimulation (TENS) is widely used as a non-pharmacological approach for pain relief in a variety of clinical conditions. This manuscript aimed to ... Read more

June 21, 2020June 21, 2020

PI 3-kinase delta enhances axonal PIP to support axon regeneration in the adult CNS.

Multiple Sclerosis Literature

Publication date: Jun 17, 2020 Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this ... Read more

June 13, 2020June 13, 2020

Indirect traumatic optic neuropathy after head trauma in adolescent male mice is associated with behavioral visual impairment, neurodegeneration, and elevated endoplasmic reticulum stress markers at acute and subacute times.

Major Depressive Disorder News

Publication date: Jun 11, 2020 Traumatic brain injury (TBI) results in a number of impairments, often including visual symptoms. In some cases, visual symptoms after head trauma are mediated by ... Read more

March 21, 2020March 21, 2020

Comparison of Analgesic Effect and Prognosis of Butorphanol and Fentanyl in Patients With Mechanical Ventilation

Opioids News

Publication date: Mar 20, 2020 ICU patients often in a strong stress environment. Various invasive procedures such as wound dressing change, sputum suction,Pull out the thoracic duct etc. At the ... Read more

March 1, 2020March 1, 2020

EGFR signaling causes morphine tolerance and mechanical sensitization in rats.

Opioids Literature

Publication date: Feb 27, 2020 The safety and efficacy of opioids are compromised as analgesic tolerance develops. Opioids are also ineffective against neuropathic pain. Recent reports have suggested that inhibitors ... Read more

February 1, 2020February 1, 2020

Oral Dimethyl Fumarate Reduces Peripheral Neuropathic Pain in Rodents via NFE2L2 Antioxidant Signaling.

Multiple Sclerosis Literature

Publication date: Feb 01, 2020 Available treatments for neuropathic pain have modest efficacy and significant adverse effects, including abuse potential. Because oxidative stress is a key mechanistic node for neuropathic ... Read more