Search Results for: Neuron

July 22, 2019July 22, 2019

Dopamine Deficiency Reduces Striatal Cholinergic Interneuron Function in Models of Parkinson’s Disease.

Publication date: Jul 16, 2019 Motor and cognitive functions depend on the coordinated interactions between dopamine (DA) and acetylcholine (ACh) at striatal synapses. Increased ACh availability was assumed to accompany ... Read more

July 22, 2019July 22, 2019

Beneficial effect of estrogen on nigrostriatal dopaminergic neurons in drug-naïve postmenopausal Parkinson’s disease.

Parkinson's Disease Literature

Publication date: Jul 19, 2019 This study aimed to investigate the potential beneficial effects of estrogen on nigrostriatal dopaminergic neuron degeneration in postmenopausal drug-nacEFve Parkinson’s disease (PD). Based on the ... Read more

July 21, 2019July 21, 2019

Taking out the protein garbage becomes more difficult as neurons age

Parkinson's Disease News

Publication date: Jul 18, 2019 (University of Pennsylvania School of Medicine) As cells age, their ability to shed harmful refuse declines. New research suggests that the deterioration of autophagy in ... Read more

July 21, 2019

Novel Tools towards Magnetic Guidance of Neurite Growth: (I) Guidance of Magnetic Nanoparticles into Neurite Extensions of Induced Human Neurons and In Vitro Functionalization with RAS Regulating Proteins.

Parkinson's Disease Literature

Publication date: Jul 16, 2019 Parkinson’s disease (PD) is a neurodegenerative disease associated with loss or dysfunction of dopaminergic neurons located in the substantia nigra (SN), and there is no ... Read more

July 21, 2019July 21, 2019

Extremely low frequency magnetic field induces human neuronal differentiation through NMDA receptor activation.

Parkinson's Disease Literature

Publication date: Jul 17, 2019 Magnetic fields with different frequency and intensity parameters exhibit a wide range of effects on different biological models. Extremely low frequency magnetic field (ELF MF) ... Read more

July 21, 2019July 21, 2019

Neuronal vulnerability and multilineage diversity in multiple sclerosis.

Multiple Sclerosis Literature

Publication date: Jul 17, 2019 Multiple sclerosis (MS) is a neuroinflammatory disease with a relapsing-remitting disease course at early stages, distinct lesion characteristics in cortical grey versus subcortical white matter ... Read more

July 17, 2019July 17, 2019

Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons.

Multiple Sclerosis Literature

Publication date: Jul 16, 2019 Autophagy defects are implicated in multiple late-onset neurodegenerative diseases including Amyotrophic Lateral Sclerosis (ALS) and Alzheimer’s, Huntington’s, and Parkinson’s diseases. Since aging is the most ... Read more

July 14, 2019July 14, 2019

Downregulation of lncRNA UCA1 ameliorates the damage of dopaminergic neurons, reduces oxidative stress and inflammation in Parkinson’s disease through the inhibition of the PI3K/Akt signaling pathway.

Parkinson's Disease Literature

Publication date: Jul 09, 2019 This study is conducted to investigate the role of lncRNA urothelial carcinoma-associated 1 (UCA1) in the protection of dopaminergic neurons in Parkinson’s disease (PD) through ... Read more

July 14, 2019

Serum secreted miR-137-containing exosomes affects oxidative stress of neurons by regulating OXR1 in Parkinson’s disease.

Parkinson's Disease Literature

Publication date: Jul 10, 2019 Recently, it has been demonstrated that microRNA-137 (miR-137) plays a vital role in the induction of oxidative stress of neurons in Parkinson’s disease (PD). Herein, ... Read more

July 13, 2019July 13, 2019

Conditioned Medium from Endothelial Progenitor Cells promotes number of dopaminergic neurons and exerts neuroprotection in cultured ventral mesencephalic neuronal progenitor cells.

Parkinson's Disease Literature

Publication date: Jul 09, 2019 Transplantation of stem and progenitor cells offers a promising tool for brain repair in the context of neuropathological disorders including Parkinson’s disease. There is growing ... Read more